Search results for "filtration"
Article
CMOs Continue to Improve Overall Biomanufacturing Performance
Many are also using or evaluating a number of technologies, including:
• Membrane-based filtration technologies
• Ion-exchange membrane technologies
• Ion-exchange technologi…
Article
Re-use of Protein A Resin: Fouling and Economics
Sofer, “Lifespan studies for chromatography and filtration media” in Process Validation, A. S. Rathore and G. Sofer, Eds. (Marcel Dekker, 2005), pp. 169-203.
20. A. S. Rathore, “Qualification of a…
Article
SEC in the Modern Downstream Purification Process
SEC, also known as gel-filtration chromatography, is a chemically inert mode of chromatography employed for biomolecule purification. Biomolecules typically should not bind to an SEC resin like they d…
Poster
Accurate comparability assessment of a biosimilar interferon in process development
This application note describes how to achieve accurate comparability assessments using Biacore™ T200 and
Amersham™ WB system in the development of a biosimilar. This is exemplified in this study…
Article
Application of Quality by Design to Viral Safety
These steps can include UV-C irradiation (6), gamma irradiation (7), high-temperature short-time treatment (6, 8) and virus reduction filtration (9, 10). These measures may be optimized to reduce smal…
Article
2014 Manufacturing Trends and Outlook
Better filtration, chromatography columns, automation, and process analytical technologies also were identified as ways to improve manufacturing efficiencies.
an Alternative:
Outsourced M…
Article
Bioprocessing Advances in Vaccine Manufacture
This trend includes 54% considering high-capacity chromatography resins; 44%, single-use filters; 38%, automated buffer dilution systems; and 35%, single-use tangential flow filtration.Other advances …
Article
Report from the Eighth International Plasma Product Biotechnology Meeting Melia Salinas, Lanzarote, Spain
He elaborated on the mechanism of virus removal in nano-filtration where transmission electron and fluorescence microscopy were used to study the distribution of the model virus in the filter. The res…