Search results for "filtration"
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Speed and Flexibility Are Dual Goals for Biopharma Operations
Other product introductions included new chromatography columns, inline process monitoring sensors, lab and pilot-scale filtration systems, and pumps and fluid handling systems. Suppliers also introdu…
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Accelerated flavivirus vaccine production with modern tools and solutions
Flavivirus vaccine development and production constitute many challenges and can be both space-and resource-consuming. This white paper gives an overview of modern tools and solutions, adding flexib…
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Evaluating E&L Studies for Single-Use Systems
For example, a bag or a filter used for the final filtration of bulk drug substance will have a significantly higher rating compared with the components used in the upstream process steps.
Figure …
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Protein Characterization Using SEC: Three Webinar Takeaways
The possibility to separate molecules by size under native conditions is powerful in protein analysis. With more than thirty years in protein science, Åke Danielsson, Research Director at Cyti…
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Advancing Single-Use Technology Through Collaboration
The end-user can then determine the contribution of dilution, and removal steps such as [ultrafiltration/diafiltration] and chromatography, in reducing the calculated levels to below acceptable limits…
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Improving Process-Scale Chromatography
Advances in technology are increasing the productivity and efficiency of commercial-scale chromatography bioprocesses.
By Cynthia Challener, PhD
Chromatography is a crucial step in the purif…
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Safety Drives Innovation in Animal-Component-Free Cell-Culture Media Technology
… as high-temperature short-time (HTST), ultraviolet (UV), and gamma radiation
• Removal—Filtration with 20-50nm membranes
• Strategic sourcing—All materials from reduced risk sources.…
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Perfusion in the 21st Century
Furthermore, protein retention has been reported when working at high densities with filtration systems. Manufacturers have access to more sophisticated media and more stable cell lines with new selec…
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An Integrated Approach to Ensure the Viral Safety of Biotherapeutics
Alternatively (or additionally), nanofiltration (20-nm pore size) of liquid solutions can be considered at the point of use.
• Liquid cell-culture media can be treated by nanofiltration (2…
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Tools for Continuous Bioprocessing Development
For example, perfusion process development experiments (21) using a 4-L working-volume Wave bag and alternating tangential flow (ATF) or tangential flow filtration (TFF) cell-retention filter, consume…