Search results for " resin"
Article
Modeling and Miniaturization: Key Topics at Successful HTPD Conference
HTPD was mainly limited to 96-well plates filled with chromatography resins used for resin selection and initial screening of running condition. Since then, HTPD in chromatography applications has bee…
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From Darwin to Recombinant Fc Multimers
Damien Bataille from LFB presented how affinity chromatography with a novel chromatography resin, VIISelect, together with a QbD approach, delivered a robust process control strategy to deliver a high…
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Unifying Continuous Biomanufacturing Operations
pointed out, if resin prices were to come down, downstream continuous manufacturing might no longer offer an economic benefit (3). Additionally, says Yvonne Genzel, PhD, team leader of upstream proces…
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Accelerated flavivirus vaccine production with modern tools and solutions
For downstream processing, modern chromatography resins offer high selectivity and excellent pressure-flow properties for high productivity inmanufacturing-scale purifications. This white paper includ…
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Evaluating E&L Studies for Single-Use Systems
Extractables studies on the chromatographic resins were already available from the vendors so all resins involved in the purification process were disconnected and excluded from the extraction study, …
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High-Throughput Process Development Handbook
Time-to-clinic and time-to-market are two key factors for successful biopharmaceutical development. Efficient development of the manufacturing process is a crucial component of the overall project…
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Technology solutions simplifying chromatography unit operations
Chromatography operations typically involve steps such as resin slurry preparation, column packing, cleaning, unpacking, and resin storage. While each of the aforementioned steps can potentially be …
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Downstream Processing Continues to Worry CMOs
A majority of CMOs are considering:
• Use of high capacity resins
• In-line buffer dilution systems
• Single-use disposable tangential flow filtration (TFF) membranes
• Single use-prep…
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ReadyToProcess™ Prepacked Columns
As a supplier of both the chromatography resin and the prepacked column, GE takes responsibility for the complete supply chain.
Watch video.
Article
A Platform Approach for the Identity Testing of Multi-Component Cell-Culture Media
A similar approach was proposed for chromatography resins in another, separate study, but employed different methods (22). As mentioned previously, compendial microbiological tests were not included i…