Search results for " media" in Articles / App Notes
Article
Continuous Manufacturing: A Changing Processing Paradigm
Even so, because perfusion involves continuously introducing fresh media, there is less accumulation of toxic waste products, degraded DNA, and other debris than is associated with products that remai…
Article
Trends in Single-use Bioreactors
Ang (Eppendorf): Certain single-use systems are capable of continuous or perfusion processes as long as there is some mechanism or method to withdraw cell-free media. Eppendorf’s BioBLU single-use ves…
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Application of Quality by Design to Viral Safety
Manufacturers of biopharmaceuticals are beginning to implement viral clearance steps in the upstream process for media and raw materials. These steps can include UV-C irradiation (6), gamma irradiatio…
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Q&As with Industry Leaders
… Andreas Castan, Strategic Technology Partnerships Leader, Cytiva
What's in Your Media? How Costly is Variability of Cell Culture Media to Your Manufacturing Process?
Megan Manzano, …
Article
Evolution of the Monoclonal Antibody Purification Platform
As shown below, while the primary recovery module is kept as part of the flow scheme, it requires optimization to work with increased solids density, media components, and other metabolites. On the ot…
Article
The use of Xcellerex™ mixing system as slurry tank when packing chromatography columns
The results show that XDM Quad Mixing System is suitable for use as a media slurry tank when packing chromatography columns.
Introduction
Xcellerex XDM Quad Mixing System is designed for co…
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Unraveling the secrets of poloxamer 188 - A webinar mystery
When an inexplicable drop in cell culture performance is linked to a batch of media, researchers race to find the culprit.
In this on demand recording we will unravel the mystery as we …
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On-demand webinar: Balancing innovation, speed, and robustness to improve efficiency in upstream process development
Watch it now, on demand! We'll cover strategies like cell line development, media development, and raw material characterization to help you make your process more efficient.
Sign up and view th…
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Webinar: Establishing a CHO-K1 cell line and cell line development process for biotherapeutics markets
Establishing a robust cell line is a critical step in the development of a biotherapeutic. But how can you meet rapid timelines when the cell line development workflow is challenged by doc…
Article
Commercial Production of Gene Therapies Using Suspension or Adherent Cell Lines
FBRs “trap” cells within a solid but permeable structure and circulates media through it, thereby ensuring adequate nutrient and oxygen distribution. The fixed-bed principle allows for cells to be gro…