Search results for " yield" in Articles / App Notes
Article
Applications of Surface Plasmon Resonance for Detection of Bispecific Antibody Activity
During process development, the goals are to obtain high product yield and a good process economy; to ensure that properties related to initial CQAs are maintained; and to secure that the process itse…
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The Metrics of Quality Culture
Indirect product-quality metrics could include environmental monitoring, water trend results, and yield rates. When establishing site metrics, the company could look at inspection history including in…
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Fluid Handling in Biopharma Facilities
On the other hand, readdressing fluid handling capacity and functionality within an existing facility can yield substantial operational and cost benefits. Here as well, conceptual work pertaining to p…
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Biopharma Advances Demand Specialized Expertise
Processing approaches won’t change in terms of technology, but there will be a greater emphasis on operational excellence to reduce costly inefficiencies and improve yields from bioprocesses. As more …
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Advanced Technologies Facilitate Scale-up and Technology Transfer
Another trend driving interest in modular technologies is a reduction in production volumes due to the switch to distributed production, increasing yields, and the trend towards personal medicine. “Sm…
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Continuous Chromatography: Trends, Definitions and Approaches
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Vaccine Development and Production Challenges Manufacturers
Researchers are looking for formulations that reduce cold-chain requirements, methods to boost process yield, and new approaches to document product quality.
Some global health advocates, however, …
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The Bullish Outlook for Biosimilars
While these strategies have yielded short-term success for some organizations, they are not sustainable. Long-term success for originator manufacturers will require a different strategic approach.
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Trends in Single-use Bioreactors
In addition, there are improved control systems that allow multiple unit operation and sophisticated feed strategies improving cell yield and increasing titer with single-use bioreactors. Ergonomic fe…
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New Era for Generic Drugs
In addition to assessing non-clinical and clinical data requirements, sponsors must weigh the costs and efficiencies of in-house production versus contract manufacturing in terms of production yield, …