Search results for " yield" in Articles / App Notes
Article
Modeling Bioreactor Performance
Analyzing with simulation scenarios, fluid processing and sequencing may yield more practical near-term results than coming up with a novel bioreactor design through modeling,” he notes.
Typically…
Article
Safety Drives Innovation in Animal-Component-Free Cell-Culture Media Technology
The new expectations challenged biologics producers to avoid all animal-sourced materials in any new processes without sacrificing the high yields and overall process performance that were commonly co…
Article
Perfusion in the 21st Century
Quality, flexibility, and cost savings are driving use of perfusion technology in biosimilars manufacturing.
By Bruce Lehr, Delia Lyons
Cell-culture technology for biopharmaceutical manufact…
Article
Downstream Processing Continues to Worry CMOs
Downstream continues to fail to keep up with the recent advances in upstream yield and titers.
Reference
1. BioPlan Associates, 13th Annual Report and Survey of Biopharmaceutical Manufacturi…
Article
Microbiological Testing: Time is of the Essence
Pressures to accelerate current and next-gen therapies are challenging traditional microbiological testing methods.
By Cynthia A. Challener
Effective microbiological testing during biopharmace…
Article
Fast Turnaround with Automated Column Packing
Packing success is, therefore, key to ensure an efficient purification process with high yield and throughput.
Packing success from the start
Today it is possible to get packing right on the f…
Article
Lessons Learned Accelerate Vaccine Development
Access to the infrastructure necessary for large-scale vaccine production is also essential, and a technology that provides high yields at low volumes is preferable,” he states.
That deep understa…
Article
A Risk-Based Genetic Characterization Strategy for Recombinant CHO Cell Lines Used for Clinical and Commercial Applications
Although the truncated LC was effectively removed through the downstream purification process, the overall purification yield was significantly reduced (to approximately 10%). A new production cell li…
Article
Antibody Production in Microbial Hosts
The authors review the status of expression of antibodies in microbial hosts and present the recent advances in the production of aglycosylated antibodies in bacteria.
By Anurag S. Rathore, Jyot…
Article
Tools for Continuous Bioprocessing Development
Ram
In semiconductor manufacturing, for example, a thorough understanding of process variation allows companies to manufacture circuits with billions of transistors at high yields. These variations…