Search results for " capture"
Article
Insider Recommendations for Getting Started with Mechanistic Modeling of Chromatography
That completely captures all of the fluid dynamics and, of course, the internal geometry of the column and system.
Once we've defined these fluid mechanical effects, we can then start to provid…
Article
Track-and-Trace Progress Benefits Supply-Chain Security Efforts
…cations, and share data electronically using electronic product code information services (EPCIS) to capture events from manufacturing to serialization [and] capping to shipping.EPCIS can capture tho…
Article
Setting Up Bioprocessing Systems for Digital Transformation
Thus, staying compliant means ensuring that the connectors between systems capture all that is needed and that they do not manipulate data. “Many organizations are looking to data lakes to help meet A…
Article
Gene Therapies Push Viral Vector Production
Other innovations, such as affinity ligands for specific AAV serotypes are being developed for use with these technologies to further enhance the resolution of the capture step. A major challenge rema…
Article
Maximizing the Effectiveness of Upstream Bioprocessing Through the Combination of Lab Informatics and Instrumentation
Given these reasons, it isn’t surprising to see why barriers to knowledge sharing and collaboration have been so hard to overcome, and how differences in terminology and the way data is captured can p…
Article
Nurturing Knowledge from Disparate Data Streams
The volume and complexity of these data make the move to electronic capture inescapable, he adds.
For many of these techniques, however, the inevitable evolution from paper-based data collectio…
Article
Single-Step, Protein A Chromatography Process for Bispecific Antibodies in Early Screening
MabSelect™ PrismA protein A resin was selected for the capture step. Most fragments could be removed as early as the capture step using gradient elution from pH 5 to 3.5, without the need for addition…
Poster
Scalable Continuous Chromatography Process for Enhanced Efficiency in Biomanufacturing
… that PCC is a robust and scalable technology: a 50-fold scale-up of a three-column PCC (3C PCC) mAb capture step within the lab-scale ÄKTA™ pcc system and a 294-fold scale-up directly from lab …
Article
The Challenge of Disruptive Technologies in Bioprocessing
An example of the latter may be the use of affinity chromatography in the capture step of antibody processes, Jagschies says.
“When we look at the biologics market dynamics for treatment of dis…
Article
Challenges in Cell Harvesting Prompt Enhancements
The upper layer captures coarse particles, and the bottom layer captures smaller particles, thus reducing premature plugging and increasing the filtration capacity (3).
Through the use of a nu…