Search results for "perfusion" in Articles / App Notes
Article
Achieving Process Balance with Perfusion Bioreactors
With rising pressure to reduce costs and streamline bioprocess development, biopharmaceutical manufacturers are exploring the application of perfusion to a wider selection of biomolecules.
“Perfus…
Article
Perfusion in the 21st Century
Now, improved continuous culture technologies such as perfusion are on the rise, as biosimilar manufacturers look for new ways to cut costs while increasing quality and productivity.
With perfusio…
Article
Perfusion Culture Using TFF or ATF as Cell Retention Method
Compared with batch or fed-batch processes, perfusion processes also allow cells to be maintained in exponential growth phase for an extended period of time and reach higher viable cell densities.
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Article
Innovations in Perfusion Bioprocessing
Furthermore, we illustrate the successful transfer of the developed perfusion process from small-scale applications to an integrated continuous bioprocess at a 50 L pilot scale
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Article
Developing a Continuous Large-Scale Perfusion Cell Culture Process
This article explores the key benefits of perfusion processes.
Article
Cytiva Introduces the Xcellerex Automated Perfusion System
16, 2020 that it is launching the Xcellerex Automated Perfusion System (APS), a device aimed at simplifying processes and reducing risks when intensifying upstream operations.
Integrated with Cyti…
Article
Designing a 1.5 L Bench-Scale Model of a Perfusion Process
Establishing an appropriate model allows for higher throughput during simultaneous operation and monitoring of several cultures at different process conditions. In this article, we discus…
Article
A Small-Scale Model to Increase Yield in Cell Culture Perfusion of mAb at Large Scale
Perfusion continues to be one such operating mode which lends itself to adding benefit at the manufacturing scale while adding complexity to the small-scale approach.
Article
Perfusion N-1 – A Way to Improve the Fed-Batch Production Process
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In this article, we show how the conventional N-1 seed train step was replaced by a high-density perfusion and how the production bioreactor can be seeded at a 10-fol…
Article
A Small-Scale Model to Increase Yield in Cell Culture Perfusion of mAb at Large Scale
Perfusion continues to be one such operating mode that lends itself to adding benefit at the manufacturing scale while adding complexity to the small-scale approach.