Search results for " growth" in Articles / App Notes
Article
CMOs Continue to Improve Overall Biomanufacturing Performance
While outsourcing of downstream operations has been on the rise, it hasn’t had quite the same growth trajectory, up from 28% in 2010 to 39% of respondents in 2015.
Upstream operational impro…
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Automated harvesting and 2-step purification of unclarified mammalian cell-culture broths containing antibodies
The growth of the segment has necessitated development of new efficient and cost saving platforms for the preparation and analysis of early candidates for faster and better antibody selection and char…
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Breakthrough Drugs Raise Development and Production Challenges
Sustainable program?
The growth in breakthrough designation requests is prompting FDA and stakeholders to examine options for refining breakthrough criteria so that FDA will be able to manage the …
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USP Stresses Pharmacopeial Standards at CPhI China
As part of USP’s commitment to the growth of the Chinese pharmaceutical industry, the Convention has built training facilities in the Shanghai Pilot Free Trade Zone. “We will strengthen our collaborat…
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Host-Cell Protein Measurement and Control
During the recombinant protein production, host cells also coproduce proteins related to the normal cell functions such as cell growth, proliferation, survival, gene transcription, protein synthesis, …
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Biomanufacturing Outsourcing Globalization Continues
Recent headlines are testament to growth in China. For example, Cytiva built two facilities in China for CMO JHL Biotech, including a KUBio modular biopharma factory in Wuhan that will house 2000-L si…
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Re-use of Protein A Resin: Fouling and Economics
Other significant attributes include the level of Protein A leachate in the pool, concentration of DNA in the pool, growth media composition, and the amount of lipids in the pool (Figure 4A).
Figu…
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Continuous Manufacturing: A Changing Processing Paradigm
Amgen, “Amgen Outlines Strategy, Growth Objectives And Capital Allocation Plans,” Press Release, Oct. 28, 2014.
12. Vertex, Form 10-K Annual Report, Filed Feb 11, 2014, http://investors.vrtx.com/s…
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Fermentation for the Future
It is also useful for the production of cytokines, growth factors, and plasmid DNA. Reinisch also notes that media costs for microbial fermentation are lower, although media costs for cell culture hav…
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New Era for Generic Drugs
Liability and labels
Meanwhile, the continued growth in generic drug market share has generated more legal challenges to product development and marketing. Recent Supreme Court decisions have raise…