Search results for " growth" in Articles / App Notes
Article
Pharma Investments Reflect Key Industry Trends
Shrinking facility size, growth of biologics, and emerging market demand influence pharma investments.
Aug 2, 2014
By: Cynthia Challener, PhD
Pharmaceutical Technology
Volume 37, Iss…
Article
Single-Domain Antibodies for Brain Targeting
…s selectively expressed on brain capillary endothelial cells such as transferrin or the insulin-like growth factor (IGF-1) by receptor-mediated endocytosis (32). An alternative strategy for enhancing…
Article
Single-Use and Continuous Processing Technologies Change Facility Design
With no waiting for cell growth and cell-culture bioreactors continuously operating, columns can be smaller than when they need to handle whole fermenter volumes at one time. Ultimately, the whole fac…
Article
Concentrating Feed—an Applicable Approach to Improve Antibody Production
Although higher concentrations of feed media could be obtained by raising pH, there was an optimal pH of feed media in which cell growth and antibody production were not adversely affected. The additi…
Article
Raw Material Variability
Common examples would be out of specification for a product critical quality attribute (CQA), slower cell growth, low titer, and evidence of extraneous matter following visual inspection.
Fixing…
Article
EMA Collaborates with HTA Assessment Networks
Within less than two years, biosimilar somatropin, the growth hormone, rose from a market share of around 20% in the country to over half.
In Germany, one of Europe’s biggest markets for biosimilar…
Article
2014 Manufacturing Trends and Outlook
The responses indicate some signs of manufacturing growth. More than half of all respondents said their companies increased biomanufacturing capacity in 2013. Less than 3% reported a drop in productio…
Article
Elucidating Biosimilars Characterization
The growth corresponds to a 20% increase from last year’s figures and accounts for approximately 2% of the overall biologics market. Although narrowly focused on only a small number of therapy areas a…
Article
Regulatory Challenges in the QbD Paradigm
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• Risk assessments
• Process vulnerabilities to microbial contamination
• Microbial growth potential of product and other process solutions
• Impact of microbial contamination on proce…
Article
Flexibility in Biopharmaceutical Manufacturing
Maintaining flexibility in biopharmaceutical manufacturing can deliver positive results.
By: Simon Chalk
BioPharm International
There is a high degree of consensus in the biomanuf…