Search results for " growth"
Article
Biosimilars to Drive Modern Manufacturing Approaches
Bernstein financial analyst Ronny Gal predicted at the Biosimilars Council conference that biosimilars will experience strong market growth during the next few years, as regulatory issues related to p…
Poster
Validation of Cytodex™ Gamma microcarrier-based virus production in single-use bioreactor systems
The results show virus titer activity was comparable for Cytodex and Cytodex Gamma and there was no observed difference in distribution or cell growth between systems.
Article
Managing Biomanufacturing Capacity Expectations
“Retirement of very old plants is being exceeded by new capacity growth, [and] overall capacity needs are growing,” notes Greg Guyer, leader in biologics development and operations at Bristol-Myers Sq…
Article
Fed-batch supplements to boost cell culture performance
Cell growth and MAb production in the fed-batch cultures were compared with batch cultures. The results demonstrate increased viable cell yields and productivity in the fed-batch cultures.
Downloa…
Article
Combining Microbioreactors and Advanced Statistical Techniques to Optimize a Platform Process for a New Host-Cell Line
Loadings on PC1 were heavily influenced by growth, osmolality, and amino acid concentrations. The feed system of the platform process was linked to the viable cell concentration. The correlation obser…
Article
Implications of Cell Culture Conditions on Protein Glycosylation
Optimum cell-culture development is achieved by working with bioreactors to enhance growth and productivity via selection of basal media and culture feeds and the timing for these feeds; optimizing bi…
Article
CMOs Continue to Improve Overall Biomanufacturing Performance
While outsourcing of downstream operations has been on the rise, it hasn’t had quite the same growth trajectory, up from 28% in 2010 to 39% of respondents in 2015.
Upstream operational impro…
Article
Automated harvesting and 2-step purification of unclarified mammalian cell-culture broths containing antibodies
The growth of the segment has necessitated development of new efficient and cost saving platforms for the preparation and analysis of early candidates for faster and better antibody selection and char…
Article
Breakthrough Drugs Raise Development and Production Challenges
Sustainable program?
The growth in breakthrough designation requests is prompting FDA and stakeholders to examine options for refining breakthrough criteria so that FDA will be able to manage the …
Article
USP Stresses Pharmacopeial Standards at CPhI China
As part of USP’s commitment to the growth of the Chinese pharmaceutical industry, the Convention has built training facilities in the Shanghai Pilot Free Trade Zone. “We will strengthen our collaborat…