Search results for " growth"
Article
From Darwin to Recombinant Fc Multimers
The expected growth from 2017-2020 is expected to be 6-8%, reaching a business size of $20 billion. IgG market will continue to dominate with 46% of market, followed by albumin, 18%, John Perkins stre…
Article
Unifying Continuous Biomanufacturing Operations
Through continuous manufacturing methods upstream, engineers have been mastering the ways to support the growth of cells to desired volumes while preserving cell viability. Downstream continuous purif…
Poster
Adenovirus production in a single-use stirring tank bioreactor system
However, scale-up using these techniques is complicated and limited by the surface available for cell growth. One alternative is to scale up the production on microcarriers. Another solution is to us…
Article
Improvements in Protein A Chromatography
Bolton recently published a paper “Role of more than 40 years of improvement in Protein A chromatography in the growth of the therapeutic antibody industry,” and also presented at the spring ACS meeti…
Article
Being Thorough When Transferring Technology
Another challenge is a high amount of dissolved CO2 in culture, if not managed carefully, can lead to high osmolality and cessation of cell growth or productivity. Additionally, non-physiological diss…
Article
Critical Quality Attributes Challenge Biologics Development
The past decade has experienced a tremendous growth in the biologics portfolio of the biopharmaceutical industry. With the advancement of knowledge in analytical sciences, protein engineering, biology…
Poster
Development of a chemically defined medium for virus vaccine production in a duck suspension cell line
The primary goal of this project was to develop a chemically defined medium that could be used in a monophasic process while supporting the growth and production of a broad spectrum of different virus…
Article
Impact of Manufacturing-Scale Freeze-Thaw Conditions on a mAb Solution
It minimizes the risk of microbial growth, increases product stability with extended shelf life, eliminates agitation and foaming during transportation, and increases flexibility during manufacturing …
Poster
Effects of feeding strategy on CHO cell performance in fed-batch cultures
The results emphasize the importance of an appropriate feeding strategy to achieve optimal cell growth and productivity.
Article
The Tide Stays High
Most publicly-traded services providers achieved revenue growth well in excess of 10% in 2016 (based on interim results), especially in those services that cater to clinical development (clinical supp…