Search results for " disposable"
Article
Automated harvesting and 2-step purification of unclarified mammalian cell-culture broths containing antibodies
The system consists of two bench-top chromatography instruments connected to a central unit with eight disposable filtration devices used for loading and filtering the cell cultures. The staggered par…
Article
Using Xcellerex™ mixing system as a slurry tank when packing chromatography columns
Further, an evaluation of the effect of the integrated, disposable mixer bag impeller on chromatography media particles was performed. The results show that XDM Quad Mixing System is suitable for use …
Article
Fluid Handling in Biopharma Facilities
Industry experts discuss challenges, trends, and innovations in fluid handling.
By Susan Haigney
Contamination prevention in biopharmaceutical manufacturing is crucial, and the proper handling…
Article
Taking a “Development-by-Design” Approach to Cell Therapies
Jun 15, 2015
By Agnes Shanley
BioPharm International eBooks
Volume 28, Issue 13
Whether outsourcing or developing cell therapies in-house, success demands a focus on quality, c…
Article
Biopharma Advances Demand Specialized Expertise
Single-use disposable bioreactors and similar single-use bioprocess equipment minimize plant downtime, which is traditionally required for line clearance and product changeover. The complexity of prod…
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Modular Manufacturing Platforms for Biologics
With single-use systems, “The changeover to another product can be swift, and potential cross-contamination can be avoided, since the product contact layers are disposable,” says Jornitz. Plus, if “ca…
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Continuous Manufacturing: A Changing Processing Paradigm
The company’s continuous “Next-Generation Biomanufacturing Facility” uses single-use bioreactors, disposable plastic containers, real-time quality analysis, and also boasts modular design. It is expec…
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Improving PAT for Biologics
The shift from classic stainless-steel equipment toward smaller production skids, most often based on disposables, is also presenting challenges for measurement methodologies, according to Backx. Fina…
Article
New Era for Generic Drugs
…cies of in-house production versus contract manufacturing in terms of production yield, media costs, disposable versus fixed production train, needed purification steps, and fill/finish arrangements.…
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Challenges and Trends in Biopharma Facility Design
Walter, The Disposable Facility and Single-Use Technology-a Solution or a Revolution?, BioPharma Asia: pp 36-49 (2012).
2. A. Pralong, Biopharma Asia Magazine 2 (1) (2013).
3. M.W.Jornitz, “De…