Search results for " disposable"
Article
Automated In-Line Buffer Preparation from Ready-Made Stock Solutions in a mAb Process Step
To further reduce the time and space required, ready-made stock solutions delivered in disposable bags were connected directly to the Inline Conditioning system and feedback regulation of the final bu…
Article
Being Thorough When Transferring Technology
Communication and taking the time to develop the process are key to successful transfer and scale up of biologics.
By Susan Haigney
Editor's note: The following is an extended version of the…
Article
Speed and Flexibility Are Dual Goals for Biopharma Operations
Bioprocessing facilities, equipment, and materials, as well as strategies to improve biopharmaceutical development and manufacturing, were featured at INTERPHEX 2017, held in March in New York City.…
Article
Cost Considerations Drive Lean Technology in Biopharmaceutical Manufacturing
By Catherine Shaffer
Four biosimilars have been approved for the market by FDA as of February 2017, and more are in the pipeline. Now that biosimilars are here to stay, manufacturers are devel…
Article
Ensuring the Biological Integrity of Raw Materials
Single-use manufacturing devices, disposable consumables, and ready-to-use reagents and media are also reducing rates of contamination in the industry.
Faster, more accurate tests are being introd…
Article
Improving Process-Scale Chromatography
“Initially, many people in the industry expected disposables to be less environmentally sound than traditional technologies, but our studies have revealed the opposite,” she observes. Most notably, si…
Poster
Scale-up and process economy calculations of a dAb purification process using ready-to-use products
Purification of a domain antibody (dAb) in a chromatography capture step was successfully scaled from laboratory to pilot scale using ready-to-use equipment and ready-made buffers. The scaled-up pro…
Article
Design and Qualification of Single-Use Systems
…integrity properties, sterilizability, drainability, incorporation into an automated platform as the disposable fluid path, etc.
• Manufacturability ensures that the SUT production equipment and …
Article
Managing Biomanufacturing Capacity Expectations
Capacity for complex therapeutics is becoming increasingly difficult to predict.
By Randi Hernandez
Demand for any given new product is typically only known after significant investments h…
Article
Lessons Learned Accelerate Vaccine Development
In addition, disposable technologies offer the potential to eliminate equipment cleaning, process cleaning validation, and cross-contamination, plus facilitate changeovers between processes, according…