Search results for " disposable"
Article
New Therapies Present Scaling Challenges
It is estimated that scale-up manufacturing solutions for cell therapies will need to generate batches of up to 2000 L (3) of product using single-use, disposable technology. Dependence on single-use …
Article
Monitoring and Control of Inline Dilution Processes
For instance, Vermunt notes that for years there has been a limitation to implementing ILD in SU systems due to a lack of suitable disposable pump and flow sensor technologies. “Today there are new SU…
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Tools and Processes for Mature and Emerging Therapies
…d processes such as restricted access barrier systems and isolators, and also recommended single-use disposable systems. Automated processing continues to play a role in high-speed applications; howe…
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What’s New in Upstream Technologies
The 550pH sensor is an electrochemical, fully disposable device with sensor stability of less than 0.005 pH change per day, which was verified by company testing. The device provides up to 10 times en…
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Biopharmaceutical Process Development: 2018 Lessons and 2019 Predictions
…Manufacturing Key to More Effective Vaccines
• Evaluation of Performance of a Disposable mAb Affinity Chromatography Column Used Over Multiple Process Cycles
• Optimization of Fed‑Batch…
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A Look at the Affinity Chromatography Landscape
A Look at the Affinity Chromatography Landscape
New ligands are being developed to meet the separation and purification needs of next-gen biologics.
By Cynthia A. Challener
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Optimizing Late-Stage and Commercial Cell-Culture Processes
Optimizing Late-Stage and Commercial Cell-Culture Processes
Late-stage and commercial biomanufacturing pose a challenge to cell-culture processing.
By Feliza Mirasol
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Article
Challenges in Cell Harvesting Prompt Enhancements
Biomanufacturers have been shifting from large stainless-steel bioreactors in the thousands-of-liters range to smaller, disposable bioreactors (2).
The need to address this bottlenecking issue …
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Process Development: What May Lie Ahead in 2018?
…ctor designs, stirring mechanisms, and sensor systems have contributed to the increasing adoption of disposable reactors from the lab to production scale,” according to BioPharm International.
20…
Article
Platform Technologies Improve Protein Expression
In addition to exploring novel production methods such as continuous processes and disposable production technology, manufacturers also heavily invest in platform technologies for protein expression t…