Search results for " single-use"
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Maximizing the Effectiveness of Upstream Bioprocessing Through the Combination of Lab Informatics and Instrumentation
The increasing popularity of single-use bioreactor systems and continuous processing techniques have brought both new opportunities and challenges to upstream bioprocessing. Together, these trends hav…
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Strategizing for Rapid Changeovers in Biologics Manufacturing
“Pre-gamma irradiated single-use flow paths for all unit operations, standardized pre-sterilized tubing assemblies to connect unit operations, and aseptic quick connectors (rather than welding or heat…
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What’s New in Upstream Technologies
Single-use sensor and adapter
Emerson’s Rosemount 550pH sensor and Rosemount 550DW dissolved oxygen (DO) sensor adapter provide improved sensor stability for single-use bioreactors and are suited …
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Improving PAT for Biologics
…e variability of raw materials (particularly living organisms), and the move from stainless-steel to single-use equipment. The recent emphasis on establishing a thorough understanding of the manufact…
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Optimizing Resin Performance with Disposable Chromatography Solutions
Consequently, the initial uptake of single-use chromatography solutions was relatively slow. Recent years have seen much greater adoption of single-use chromatography, including both systems with sepa…
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Process Development: What May Lie Ahead in 2018?
They were very interested in a discussion about how single-use systems have great potential in the manufacture of antibody‑drug conjugates.
Single-Use in Full Force
Single-use technology con…
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Cell-Culture Advances Test Bioreactor Performance Models
Smith, staff engineer for single-use technologies in the BioProduction Division of Thermo Fisher Scientific.
In particular, the inexpensive computing power and excellent computational talent ent…
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Achieving Process Balance with Perfusion Bioreactors
The benefits of single-use technology align well with continuous processing. “The inherent advantages of single-use systems compared to stainless-steel are speed and flexibility, which are also the ma…
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State of the Biopharmaceutical Industry: Lessons from 2018 Survey Data
For example, our studies have shown rather consistent incremental increases in upstream cell culture titers over the past three decades; and it took well over a decade for single-use equipment to atta…
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Improving Process-Scale Chromatography
The development of new resin chemistries including enhancements to Protein A for monoclonal antibody (mAb) capture, increasing use of automation, implementation of single-use technologies, and explora…