Search results for " single-use"
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Continuous Manufacturing: A Changing Processing Paradigm
While adoption of continuous processes may seem slow, single-use technologies themselves are still fairly new. Single-use process technologies took “20 years to be fully adopted and accepted in clinic…
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Technology Innovations Improve Process Chromatography Performance
Although significant work has been done in upstream bioprocessing to remove bottlenecks through the implementation of single-use technologies, better characterization of raw materials, and the use of …
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A Q&A with Eric Langer: CMOs Embrace New Technology
In our 13th Annual Report of Biomanufacturing, of the 21 areas of innovation tested, we found CMOs more interested in: chromatography, single-use probes and sensors, disposable chromatography, instrum…
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Bioprocessing Advances in Vaccine Manufacture
In the BioPlan study, vendors were asked if they provide sufficiently scalable single-use disposables and techniques. Overall, 53% of the industry considers scale to be a significant adoption restrict…
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Biomanufacturing: Demand for Continuous Bioprocessing Increasing
… are generally not yet ready yet for commercial-scale adoption (other than adoptions performed using single-use upstream equipment generally limited to 2000-L scale).
Outsourcing and continuous b…
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Design Considerations for a Commercial Cell and Gene Therapy Facility
Already well-established, mAb production is typically batch-oriented (in this way, making it similar to allogeneic cell therapy production) and characterized by larger single-use bioreactor skids with…
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Modular Manufacturing Platforms for Biologics
They can also include configurable skids; process modules/skids based on single-use equipment; or unit operations within modules, such as suites made exclusively for aseptic filling of prefilled syrin…
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Biopharmaceutical Process Development: 2018 Lessons and 2019 Predictions
Clearly, industry members (including Process Development Forum readers) are extremely interested in learning about what these solutions have to offer, but the adoption of single-use systems is still c…
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Automating Bioprocesses
By Jennifer Markarian
Both upstream and downstream biopharmaceutical processes have conventionally used stainless-steel equipment, but use of single-use systems (SUS) is becoming more established.…
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Downstream Processing Continues to Worry CMOs
Interestingly, two of the areas in which there were sizable declines in participation this year—investigating single-use products and developing processes with fewer steps—are CMO favorites. When resp…