Search results for " single-use"
Article
A Plastic Pipeline for Commercial Bioprocessing?
The maturation of single-use technologies presents commercial bioprocessing options for small-volume drug products.
By Rita C. Peters
Nejron Photo/Shutterstock.com
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Article
The New World of Biopharmaceutical Manufacturing
Without question, single-use (i.e., disposable) technology has been one of the most significant changes. Advantages of single-use technology include greater flexibility, reduced resources for cleaning…
Article
Improving mAb Manufacturing Productivity by Optimizing Buffer and Media Prep Process Flow
Solid or hydrated buffers and salts that come ready-to-dispense in single-use bags and buffer preparation using single-use systems, reactors, and in-line dilution can both help eliminate or reduce wei…
Article
Fluid Handling in Biopharma Facilities
Facility layout can help determine how companies handle fluid transfer and storage, and increased use of modular facilities and single-use systems (SUS) in the production and transfer of sterile fluid…
Article
Challenges and Trends in Biopharma Facility Design
BioPharm International spoke with Daniella Kranjac, head, evaluation and offering, Enterprise Solutions, at Cytiva; Mario Philips, president of Single-Use Technologies at Pall Life Sciences; Par Almhe…
Article
Advanced Technologies Facilitate Scale-up and Technology Transfer
Single-use solutions
One of the most efficacious ways to revamp older processes as required by FDA is to upgrade with single-use technologies, according to Helene Pora, vice-president of single-us…
Article
Overview of a scale-up of a cell-based influenza virus production process using ReadyToProcess equipment
…am and downstream processes for the production of a cell based live attenuated influenza virus using single-use ReadyToProcess technology (Fig 1).
Introduction
Egg-based production is the…
Article
Reconciling Sensor Communication Gaps
Single-use systems generally suffer from a “sensor gap” related to the need to balance measurement accuracy against the well-known benefits of single-use processing, including the avoidance of cleanin…
Article
Advances in Sterilization Technologies for Overcoming Viral-Vector Manufacturing Challenges
…grity test (PUPSIT) and a post-use integrity test in situ, the potential for leak development within single-use manifolds during installation or processing, and the need to minimize hold-up volumes, …
Article
Setting Up Bioprocessing Systems for Digital Transformation
Single-use systems risks
The same principles and need for data integrity apply to single-use systems but at a higher volume, says Lenich. He emphasizes that, in addition to maintaining data integr…