Search results for "Upstream" in Articles / App Notes
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Save the date for HTPD 2025
We are pleased to announce the 7th International Conference devoted to High-Throughput Process Development (HTPD) and smart PD, to be held May 26–29 2025 in Uppsala, Sweden.
The program and…
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Report from the 6th International HTPD Conference
Since then, HTPD in chromatography applications has been well established among most biopharmaceutical companies but has also expanded to upstream and cell culture screening as well as to formulation …
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Trace metals getting you down? Learn what’s really in your cell culture media
Heavy metal might have a place in your music playlist, but heavy metals should stay out of your cell culture media. Heavy metal impurities in your media can have a drastic effect on cell vi…
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Process Development and Control for New Modalities
Increasing molecular diversity leads to more challenges in process development and control. Advancements in technology for manufacturing and online analytical monitoring have not caught up…
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Scaling a mAb production process to Xcellerex bioreactors
Moving a monoclonal antibody production process from a microscale bioreactor to the Xcellerex XDR single-use platform.
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Antibody Production Workflow
Explore the workflow here >>
Antibody-based therapies have evolved beyond monoclonal antibodies (mAbs) to include bispecific antibodies, antibody fragments, antibody-drug conjugates (ADCs), and m…
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A Small-Scale Model to Increase Yield in Cell Culture Perfusion of mAbs at Large Scale
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As process intensification is adopted into large-scale manufacturing, the responsibility on scale-down models to accurately represent the expanded operating space quic…
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Process Development: Go Smarter, Go Faster! Available on Demand
The upstream and downstream case studies presented in these workshops will help you to:
• Improve efficiency: Save time during process development with the latest techniques and ways of working…
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Accelerating an Orphan Therapy to Market
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This case study shares the work of Cytiva’s Fast Trak Services team to help accelerate development of a process for cGMP production of material for toxicology studies.…
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Cell Culture Media Considerations and Optimization for Improved Titers and Protein Quality
Peggy Lio, Cytiva
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Peggy Lio, Senior Director of Global Cell Culture Services at Cytiva, explores the evolution of b…