Search results for "purification" in Articles / App Notes
Article
Managing Biomanufacturing Capacity Expectations
BioPlan found that the development of more efficient single-use products, better downstream purification technologies, the introduction of continuous downstream operations, and increased modularizatio…
Article
Fast Turnaround with Automated Column Packing
Packing success is, therefore, key to ensure an efficient purification process with high yield and throughput.
Packing success from the start
Today it is possible to get packing right on the f…
Article
Your Reliable Downstream Bioprocessing. Our Proven AxiChrom Columns
The goal for biopharmaceutical manufacturers is to develop a process that will deliver material for clinical trials quickly and smoothly, achieve success in these trials, and scale up to commercial …
Article
Lessons Learned Accelerate Vaccine Development
High-throughput and single-use technologies are also being leveraged to accelerate key aspects of manufacturing processes, such as determination of appropriate media, resins for purification, formulat…
Article
Going Small to Achieve Success on the Commercial Scale
Meizinger, a process engineer in Genzyme’s Purification, Manufacturing Science, and Technology Laboratory.
Scale-down models are used in the development of nearly every unit operation in the overa…
Article
Biopharma in 2015: A Year for Approvals and Innovations
…E Bioreactor™ systems
The Use of Dynamic Control in Periodic Counter-Current Chromatography
Purification Strategies to Process 5 g/L Titers of Monoclonal Antibodies
Trends in Single-use Bior…
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Implications of Cell Culture Conditions on Protein Glycosylation
Production is fast using simple media; however, purification can be challenging. Rapid production of proteins with primitive glycosylation can be achieved using yeast. Insect cells, generally used wit…
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Capto™ Core 700 in Vaccine Processing
The aim with this white paper is to discuss the advantages of using Capto Core 700 in virus purification compared to size exclusion chromatography (SEC), a technique commonly used in several vaccine…
Article
Best Practices in Qualification of Single-Use Systems
Culter, Protein Purification Protocols, Second Edition (Humana Press, 2004).
14. F. Jameel and S. Hershenson, Formulation and Process Development Strategies for Manufacturing Biopharmaceuticals (W…
Article
Fluid Handling in Biopharma Facilities
For example, as the productivity of upstream processes has improved, the need to run a greater number of cycles through purification equipment has also increased, which increases buffer consumption. A…