Search results for " fluid"
Article
Sterilization Trends for Single-Use Consumables
VHP is used to frequently decontaminate exterior surfaces of SU systems such as in isolators, but is not amenable for sterilization of internal fluid paths.
E-beam sterilization is another form of…
Article
Considerations in depth filter scale-up
The filter media thickness, pore size distribution, and adsorptive capacity make them the ‘go-to’ technology in harvest applications where a product is separated from a complex cell culture fluid.
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Article
HTPD 2023 conference is coming up. What will be discussed and what happened last time?
We are also pleased to have Professor Martina Micheletti giving a plenary talk on the topics of bioprocess fluid dynamics.
The Organizing Committee, invite you to the 6th HTPD meeting and look fo…
Article
Digitalized PD: Speeding up downstream process development
Mechanistic models enable the simulation of chromatography processes based on fundamental natural laws, such as fluid dynamics and thermodynamics. In silico simulations of chromatography proce…
Webcast
Xcellerex™ X-platform bioreactor live virtual demo
In this virtual workshop Ken Clapp will explain how we developed the Xcellerex™ X-platform bioreactors using a verified computational fluid dynamics model. Thomas Falkman and Sanna Tronnersjö will joi…
Article
Xcellerex™ X-platform bioreactor live virtual demo
In this virtual event, Ken Clapp will explain how we developed the Xcellerex™ X-platform bioreactors using a verified computational fluid dynamics model. Thomas Falkman and Sanna Tronnersjö will join …
Article
Accelerating VLP purification process development
In contrast, mechanistic models describe the transport of sample components using fluid dynamic and thermodynamic principles. Further, they allow for efficient process optimization in silico.
R…
Article
Mechanistic Modeling: Current Advantages and Future Opportunities in Biopharmaceutical Process Development
Only the fluid dynamic parameters must be adapted to the new scale. The actual interactions of molecules with the ligands on the resin do not change.
In summary, I am convinced that soon, modelin…
Article
Eliminating Residual Impurities Starts with a Strategic Plan
Chandrasekaran notes that most conventional detectors lack the sensitivity to accurately measure residual impurities in process fluids. “Developing a non-denaturing method is critical to avoid inaccur…
Article
Biomanufacturing: Demand for Continuous Bioprocessing Increasing
The classic and still predominant approach to bioprocessing, both upstream and downstream, remains batch processing, with manufacturing batch fluids essentially moving incrementally en-masse from one …