Search results for " hybrid" in Articles / App Notes
Article
Single-use Bioreactors Have Reached the Big Time
He notes that often for multiproduct facilities with up to 2000 L per bioreactor train, single-use systems are more attractive, while stainless steel or hybrid approaches are typically better suited f…
Article
Automating Bioprocesses
Automation of stainless-steel systems and single-use systems differs in complexity.
By Jennifer Markarian
Both upstream and downstream biopharmaceutical processes have conventionally used st…
Article
Improving Process-Scale Chromatography
In the immediate future, downstream bioprocessing will likely involve hybrid solutions with both single-use and stainless-steel equipment and limited linkage of unit operations.
While there are no…
Article
Advanced Technologies Facilitate Scale-up and Technology Transfer
“For established facilities, modular processing units enable a quick and easy transition to the hybrid facility format, while for new facilities, they are making the fully flexible single-use facility…
Article
Use of Multivariate Data Analysis in Bioprocessing
A hybrid electronic tongue system based on the various potentiometric/voltammetric sensors and appropriate MVDA techniques has been used to provide correct qualitative and quantitative classification …
Article
Ligand-Binding Assays and the Determination of Biosimilarity
BLI also allows for hybrid binding for quantitative ELISA-like binding determinations, which may be applicable for PK/PD bioanalytical analyses, according to Sadick.
Selection and design challenge…
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Challenges and Trends in Biopharma Facility Design
This [trend] ranges from hybrid concepts, where stainless steel and single use are both used for production, to almost completely single-use, fluid-path approaches.
In my opinion, the coming years…
Article
Q&As with Industry Leaders
Discovering the unknown: How does in silico process development change PD scientists’ work?
Jeanne Linke Northrop, BioPharm International
Nora Ketterer, Manager, Modeling Services…
Article
Comparing Protein A Resins for Monoclonal Antibody Purification
The methodology for the production of monoclonal antibodies from a cell line by hybridization of mouse myeloma and mouse spleen cells from an immunized donor was first published in 1975 (1). As a tech…