Search results for " hybrid" in Articles / App Notes
Article
Labeling of Biosimilars
The current position on labeling by EMA is based on a 2012 guideline (5) covering generic medicines, hybrids, and biosimilars. This guideline states that, as with generic drugs, the biosimilar’s summa…
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Trends in Single-use Bioreactors
It’s generally easier to interconnect single-use products when and where desired as opposed to trying to hybridize with existing stationary steel systems.
Galliher (Cytiva): It depends. On the one…
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2014 Manufacturing Trends and Outlook
Single-use systems and other technologies drive process efficiencies, but there is room for improvement.
In a recent survey of current trends and practices in biopharmaceutical manufacturing…
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Paring Down Impurities in Downstream Processing
Bioreactors to house these systems might be stirred-tank, air-lift, fixed-bed, hollow-fiber perfusion, or suspension, perhaps even hybrid combinations thereof. All of these lead to a gamut of membrane…
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Benefits of DoE vs mechanistic modeling
You will learn that, quite often, these methods work hand in hand in a hybrid setup to improve your process development!
Watch this webinar on-demand
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Pandemic Alters Policies and Practices for Drug Development and Regulation
By Jill Wechsler
The need for medicines to combat COVID-19 has impacted the way regulatory agencies carry out their operations.
Drug development and regulati…
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Strategizing for Rapid Changeovers in Biologics Manufacturing
Ribault does add, though, that if a hybrid approach is used, all aspects including equipment and sampling, need to be taken into account to ensure there are no bottlenecks that can slow down the chang…
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Mechanistic Modeling: Current Advantages and Future Opportunities in Biopharmaceutical Process Development
Molecular dynamics simulations increase our scientific understanding, while a hybrid of mechanistic and statistic models allows to better cope with uncertainty, noise and trends over production cycles…
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Biomanufacturing: Demand for Continuous Bioprocessing Increasing
Use of continuous bioprocessing is likely to further increase with the arrival of more hybrid systems that use bolt-on-type technology, which retrofit components unit operations for existing systems. …
Article
Methods Accelerate Biosimilar Analysis
The new generation of mass spectrometers, including time-of-flight (ToF) instruments, as well as hybrid systems such as quadrupole (Q)–ToF, ion trap–ToF or ToF–ToF, and orbital ion trap mass spectrome…