Search results for " E. coli" in Articles / App Notes
Article
What’s New in Upstream Technologies
Recent upstream processing innovations include enhanced sensor technology, single-use bioreactors, and automated cell culture systems.
By Amber Lowry
SCIENCE PHOTO - STOCK.A…
Article
Recent Advances in the Use of Exoglycosidases to Improve Structural Profiling of N-glycans from Biologic Drugs
Recent Advances in the Use of Exoglycosidases to Improve Structural Profiling of N-glycans from Biologic Drugs
Analytical exoglycosidases are transitioning from being largely academic tools to being s…
Article
Performance of Single-Use Xcellerex™ XDR‑500 MO and XDR‑50 MO Stirred-Tank Fermentor Systems
Domain antibody production in E. coli was used as the model process. Fermentations were performed as fed‑batch processes, with glycerol feed and a two‑stage induction strategy. The presented data …
Article
Advanced Technologies Facilitate Scale-up and Technology Transfer
Single-use and modular technologies plus continuous manufacturing are increasingly important to biopharma scale-up and tech transfer.
Jun 01, 2015
By Cynthia A. Challener
BioPharm Inte…
Article
High-Throughput Process Development in an Historical Environment
The challenge in the very first HTPD Olympiad 2014 was to develop a purification process for a Dab expressed in E. coli using high-throughput workflows for maximized Dab purity and yield. Six teams si…
Article
Trends in BioPharma Approvals in 2013
…alian cell lines (seven in CHO cells, one in Sp20), six are produced in yeast-based systems, four in E. coli and two in insect-based systems. These approvals reflect trends in expression systems used…
Article
Comparing Protein A Resins for Monoclonal Antibody Purification
A prototype Protein A resin is evaluated for purification performance, reusability, and cost performance.
With greater economic pressure on monoclonal antibody (mAb) production for therapeutic …