Search results for " E. coli" in Articles / App Notes
Article
Preclinical Evaluation of Product Related Impurities and Variants
Preclinical Evaluation of Product Related Impurities and Variants
The approaches for sample preparation of preclinical evaluation of safety and efficacy are addressed taking into consideration the s…
Article
Platform Technologies Improve Protein Expression
Platform technologies facilitate development and accelerate commercialization of protein therapeutics.
By Cynthia A. Challener
Speed to market is essential in the biopharmaceutica…
Article
Safety Drives Innovation in Animal-Component-Free Cell-Culture Media Technology
The E. coli cultures may have been fed with culture media containing animal-sourced materials. The frozen cell bank may have been cryopreserved using animal-sourced materials. There may have been anim…
Article
Host-Cell Protein Measurement and Control
Jun 01, 2015
By Fengqiang Wang, PhD, Daisy Richardson, Mohammed Shameem
BioPharm International
Volume 28, Issue 6, pg 32–38
Host-cell proteins (HCPs) constitute a major part of proce…
Article
Single-Domain Antibodies for Brain Targeting
Single-domain antibodies are emerging as credible alternatives due to their target specificity, high affinity, and cost-effective recombinant production.
Smaller recombinant antibody fragments a…
Article
Bioprocessing Advances in Vaccine Manufacture
Advances in techniques and single-use systems are revolutionizing vaccine manufacturing.
The vaccine industry, particularly, in major Western markets, continues to be dominated by a few majo…
Article
A Platform Approach for the Purification of Domain Antibodies (Dabs)
First, a capture step using Capto™ L was used to reduce E. coli host cell proteins (ECP) and endotoxin levels.
Next, a polishing step using Capto MMC ImpRes further reduced ECP and endotoxin l…
Article
Stirring up the fermentation game
Microbial fermentation in single-use Xcellerex™ XDR-50 MO fermentor system
This application note describes the performance of a single-use Xcellerex XDR-50 bioreactor system when used in culti…
Article
Digitalization: The Route to Biopharma 4.0
Modeling Concentration Gradients in Fed-batch Cultivations of E. Coli—Towards the Flexible Design of Scale-Down Experiments. J. Chem. Technol. Biotechnol. 2019, 94 (2), 516–526. DOI: 10.1002/jctb.5798…
Article
Testa Challenge 2020 Attracts Leading International Bioprocessing Innovators
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Six bioprocessing innovators have successfully completed the inaugural Testa Challenge 2020. Held over an intensive week in the Testa Center located at Cytiva´s Uppsala…