Search results for " resin"
Article
Purify App: Finding What You Need for Protein Purification
…nfigure an ÄKTA system to match your application?
Visit the NEW purify app to:
• select resins, prepacked columns, and empty columns
• configure and visualize ÄKTA systems in …
Article
Scaling Up Novel Therapies
In addition, the equipment footprint was reduced by four or five fold, and the systems enabled, at large scale, a 40–50% savings in Protein A resin use, he says.
High operational and capital c…
Article
Process Economy Simulations on a Protein A Capture Step
Calculations show that normalized cost per batch can be reduced by 75% using MabSelect PrismA compared with the predecessor MabSelect SuReTM resin.
Learn more
Poster
Rapid Process Development of a CIEX Step for a Biosimilar
A standardized workflow was adapted using a high throughput process development (HTPD) approach: chromatography resin and running conditions were selected based on experience and adapted to meet requi…
Article
Mechanistic Modeling of Preparative Ion-Exchange Chromatography
…mechanistic model that is capable of describing mass transfer at the bead level for a chromatography resin and can be executed using a personal computer. Ion-exchange chromatography (IEC) is a major …
Poster
Collaborating to address the bioburden challenge
To meet this challenge, Cytiva is committed to continuous improvement of its chromatography resins to enable delivery of products without detectable bioburden. For example, development of Protein A re…
Article
Development of column packing methods based on pressure flow measurements
A typical problem to be addressed during scaleup is the loss of wall support for the chromatography resin as a result of the large change in aspect ratio, causing larger compression of the resin and a…
Article
High-Throughput Process Development in an Historical Environment
HTPD approaches in downstream goes beyond chromatography
The approaches in downstream process development, with screening of chromatography resins and parallel screening of optimal process conditi…
Article
Q&As with Industry Leaders
…
Jeanne Linke Northrop, BioPharm International
Emma Lind, Product Manager, Chromatography Resins, Cytiva
Optimizing your Cell Culture Process to Improve Productivity
Jeanne …
Article
Trends in Downstream Bioprocessing
In addition, while many firms would like to avoid the high cost of Protein A affinity resin, most find it difficult to make such changes to their processes, and their reluctance is compounded by the f…