Search results for " resin"
Article
Single-Use for Downstream Chromatography: Benefit or Hindrance?
Resin fouling
Another unmet need for biopharmaceutical manufacturers is technology that reduces the cost of resins (3), to allow for greater use of single-use systems to address the resin fouling t…
Article
Exosome isolation by tangential flow filtration and size exclusion chromatography
…s followed by gentle size exclusion chromatography (SEC) with our next-generation Cytiva™ superSEC resin. We found that:
- Cytiva™ superSEC resin enriched exosomes from impurities compared to lega…
Article
Chromatography for the Diversified Antibody Pipeline
… recently launched—the MabSelect VL is more alkali stable, which is expected from a chromatography resin for manufacturing. The biopharmaceutical industry is engineering for separation by making the …
Article
Cytiva Advances Fiber Chromatography Technology with New Launch
Fibro PrismA uses the same chromatography systems, infrastructure, and ligands as resin chromatography, which allows for simple transition into existing biomanufacturing facilities.
The Fibro tech…
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Updating Viral Clearance for New Biologic Modalities
… in higher levels of viral clearance as well, he says, pointing to MilliporeSigma’s chromatography resin platform, Eshmuno, as an example of a product that offers improved separation of molecules fro…
Article
A Closer Look at Affinity Ligands
This reduces the resin lifetime and introduces a process related impurity into the product mainstream. Leached protein A is considered a CQA (critical quality attribute) to measure for with a release …
Article
Chromatography innovations for the diversified antibody pipeline
Our MabSelect™ VH3 affinity resin interacts with the variable heavy chain of the VH3 sequence family of human antibody, delivering high binding capacity and efficient separation of product-related imp…
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Report from the 6th International HTPD Conference
HTPD was mainly limited to 96-well plates filled with chromatography resins used for resin selection and initial screening of running conditions. Since then, HTPD in chromatography applications has be…
Article
As the therapeutic pipeline diversifies, chromatography toolboxes are expanding.
Cytiva expands the antibody capture resin toolbox and has recently announced MabSelect™ VH3 affinity resin. MabSelect VH3 uses an engineered protein A resin that interacts only with the variable heavy…
Article
A Platform Approach to Purification of Antibody Fragments
However, with recent developments of novel affinity chromatography resins, there are new emerging possibilities. Here, we present affinity chromatography resins that offer the possibility of a platfor…