Search results for " resin"
Article
Quality by Design in Biotherapeutics Purification: Understanding and Addressing Sources of Process Variability
This white paper summarizes information around resin variability, serving as a reference and providing support for developing robust purification processes for biopharmaceuticals.
Article
Raw Material Variability: The Need for Deeper Process Understanding
The focus lies on chromatography resins.
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Article
Fundamentals of Hydrophobic Interaction Chromatography
This article explores the fundamentals and applications of hydrophobic interaction chromatography using Capto™ resins to increase productivity.
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Article
Intensified Chromatography Strategies
The blockbuster drug era is over and drug manufacturers are now striving for a more diversified portfolio by targeting a greater number of monoclonal antibody (mAb) products at lower production volu…
Poster
Reduce Risk of Failure in Your Virus Clearance Study by Choosing Robust Scale-Down Chromatography Tools
For chromatography steps, using a scale-down model limits the amount of sample and resin used, lowering the cost for the study. As viral clearance studies are often cost and time consuming, it is esse…
Article
Selectivity in Size Exclusion Chromatography (SEC): It’s Much More than Average Pore Diameter (Å)
Describing the pore of a size exclusion chromatography resin with a single number such as average pore diameter is an oversimplification. The formation of pores is dependent on complex combinations of…
Article
New Guide for Packing HiScale, XK, and Tricorn Columns
This guide summarizes parameters for packing small-scale HiScale™, XK, and Tricorn™ columns with Capto and MabSelect resins from Cytiva.
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Article
Supply Chain Challenges for Single-Use Systems
Bulpin (MilliporeSigma): Resin and film suppliers are critical to the quality control of single-use consumables. These suppliers must have a good understanding of the requirements needed for the bioph…
Article
Reduce Hands-On Time in Your Ion Exchange Chromatography Runs
Optimization and improvements in ion exchange chromatography can be time consuming. Luckily, there are several tools that greatly facilitate this. Explore four valuable tips for reducing IEX hands-on …
Article
Biopharmaceutical Process Development: 2018 Lessons and 2019 Predictions
…Cell Line
• How to Determine Dynamic Binding Capacity (DBC) of Chromatography Resins