Search results for " resin"
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Developing a Closed, Connected Single-Use mAb Purification Process
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Learn more on this case study to set up a closed and connected single-use monoclonal antibody (mAb) purification process that addresses a perfusion upstream process. In the Pr…
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Process Development: 2020 Reflections and 2021 Possibilities
More specifically, the effect of chromatography resin attributes and how to identify which parameters and interactions to focus on during process characterization studies proved to be of great interes…
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Start-to-Finish Connected Manufacturing
That’s why we are demonstrating our mAb process that tested the performance of a new Xcellerex automatic perfusion system (APS) bioreactor, compared resin and fiber-based chromatography, and utilized …
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Cytiva Invests $500 Million Over 5 Years to Expand Global Capacity
Other elements of the Uppsala investment include a capacity extension of Sephadex resin, which sets up additional facilities for in-house manufacturing, and the development of automation and digitaliz…
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Platform for Purification of VHH-type Antibody Fragments
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Protein A affinity chromatography resins have been used to purify monoclonal antibodies (mAbs) by the bioprocess industry at all scales for a long time. Howev…
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Strategizing for Rapid Changeovers in Biologics Manufacturing
Stoll adds that some product-dedicated equipment must also be installed, in particular chromatography columns with packed resin for drug substance purification. “All these activities may potentially b…
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Improving Capacity in DNA Plasmid Purification
Join Tony Hitchcock on May 6, 2020 to learn more about this critical market and how Cobra Biologics is working with Cytiva to develop a modern chromatography resin to help meet the demand.
Reg…
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Cytiva and GoSilico Agree to Co-market ChromX™ Mechanistic Modeling Software
The agreement facilitates the adoption of ChromX™ by scientists and users of resins, columns, and chromatography systems into their downstream process-development workflows to accelerate development…
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The Evolution of Supply Chain Security: Increasing Focus on Raw Material Variability
An increase in the development of biological and patient-specific drugs has also reinforced the demand for heightened raw material control.
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Purification of Plasmid DNA
By switching to modern chromatography resins, Cobra Biologics was able to increase binding capacity and flow rates up to 50% to address the increasing demands for high quality plasmid DNA.
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