Search results for " resin"
Article
Developing a HIC polishing step for removal of mAb aggregates
It includes:
- The use of HTPD plates to select the optimal resin as well as running conditions
- The use of a design of experiments (DoE) to optimize the running conditions
- A Monte Carlo simul…
Article
How to Use Multiwell Plates With Manual Operation
High-throughput tools like PreDictor™ plates prefilled with chromatography resins make it possible to explore a large characterized space for optimizing process conditions. They save time and require …
Webcast
Optimizing a HIC step with HTPD
This webinar discusses a step-by-step workflow for optimizing a hydrophobic interaction chromatography (HIC) step.
Article
Webinar: Optimizing a HIC step with HTPD
This workflow includes the use of high-throughput process development (HTPD) plates to facilitate the choice of resin and initial conditions for column chromatography, and a design of experiments (DoE…
Article
Choose your Optimal Wavelength for Chromatography
ÄKTA™ chromatography systems and resins offer a wide range of solutions for isolating and purifying target molecules from research, through process development and manufacturing. With a variety…
Article
Download your Mechanistic Modeling eBook
For example, this methodology uses differential equations that describe how molecules move between resin beads and inside the bead pores. It also uses adsorption isotherms to quantify how molecules co…
Article
Optimization of a HIC step for recombinant protein purification
Follow this step-by-step high-throughput process development (HTPD) workflow to determine the optimal resin and initial conditions for hydrophobic interaction chromatography (HIC).
…
Article
Capture of Bispecific Antibodies and Removal of Product-Related Impurities
In this article, Cytiva presents data on applications using MabSelect™ VL protein L resin with novel selectivity to purify challenging entities.
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Article
New hydrophobic interaction chromatography (HIC) handbook
The role of this technique in protein purification in the lab and at bioprocess scale, the principle of the technique, and the equipment and resins needed are described in this detailed handbook.
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Article
Chromatography innovations for the diverse antibody pipeline
In this video Josefin Bolik, global product manager — antibody capture at Cytiva, presents how to select resins for your antibody variant purification project.
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