Search results for " bioprocess" in Articles / App Notes
Article
Being Thorough When Transferring Technology
Communication and taking the time to develop the process are key to successful transfer and scale up of biologics.
By Susan Haigney
Editor's note: The following is an extended version of the…
Article
Mechanistic Modeling of Preparative Ion-Exchange Chromatography
With the advent of quality by design, there have been renewed efforts toward gaining a deeper process understanding through mechanistic modeling of key bioprocess unit operations.
Researchers have…
Article
Ensuring the Biological Integrity of Raw Materials
Wisher, Bioprocess Int. 11 (9), pp. 12–15 (October 2013).
3. O.-W. Merten, Cytotechnol. 39, pp. 91–116 (2002).
4. J.G. Victoria et al., J. Virol. 84 (12), pp. 6033–6040 (June 2010).
Article
Evaluating E&L Studies for Single-Use Systems
Colton, Bioprocess Int. (supplement) 7(1), 88-94 (2009).
5. BPOG, Best Practices for Mitigating Risk from Leachables In Single-Use Systems, www.biophorum.com, available in January 2017.
Article
Technical and Process Economical Aspects of Using Capto™ Q and ReadyToProcess™Adsorber Q in mAb Polishing
In a bioprocessing setup, ReadyToProcess Adsorber membranes enable elimination of typical bottlenecks, such as facility fit, processing time, cleaning procedures, and overall changeover times.
At …
Article
Biosimilars to Drive Modern Manufacturing Approaches
“Advanced bioprocessing is beginning to take off,” she observed, acknowledging that innovator firms largely are taking the lead in this area. But she believes that the demand for affordable alternativ…
Article
Mixing dynamics in a large volume single use mixer
Large volume single-use technology mixers can be used for mixing operations throughout the entire bioprocess workflow. Large-volume mixers are mainly required in clinical three-scale and production…
Article
Perfusion in the 21st Century
Rader RA, Bioprocessing Journal 13 (1): 43-49 (2014).
7. D. Lyons et al., “Modeling Perfusion at Small Scale Using ambr15,” presented at Integrated Continuous Biomanufacturing II, San Francisco, C…
Article
Generating a Fully Processed Antibody
Bleck, Bioprocess J. 5, pp. 36–43 (2007).
About the Authors
Gregory Bleck is global head of R&D biologics; Dona York is director of upstream process development; and David Rabuka is global h…
Article
Managing Biomanufacturing Capacity Expectations
The change can become more complicated if there is a change in product type, which may even require a completely different facility, says Tom Ransohoff, vice-president and principal consultant at BioP…