Search results for " connected" in Articles / App Notes
Article
Getting a Handle on Biopharma’s Most Critical Quality Attributes and Quality Control
While the multiple attributes method gains ground and traditional lab methods improve, broad efforts are underway to determine biopharmaceuticals’ most significant critical quality attributes and en…
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Reliability Rooms and the Move to Proactive Supply Chain Management
In the future, the RRs will become increasingly connected and data will need to be collected faster. At this point, RRs are proving to be a key process and capability to help ensure that the o…
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The New World of Biopharmaceutical Manufacturing
Today, buffers are held in bioprocess containers and unit operations are connected with tubing. Chromatography columns can be disposable or can be replaced by single-use membrane adsorbers. In the pas…
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Automating Bioprocesses
For example, tubing needs to be connected and operators must make sure that nothing leaks. All parts that come into contact with the product need to be tracked, including disposable parts and reusable…
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Improving Process-Scale Chromatography
While there are no approved downstream processes using continuous chromatography yet reported, according to Ljungqvist straight-through processing (STP), in which two or more chromatography steps are …
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Modular Manufacturing Platforms for Biologics
“The cleanroom space is accessible via air locks within the pod, which are connected to a classified corridor,” he says. This infrastructure is unlike stick-built cleanrooms, which are interconnected …
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Trends in Single-use Bioreactors
Representatives from industry supplier companies address innovations, reliability, barriers to adoption, and the role of singIe-use bioreactors in bioprocessing.
By: Randi Hernandez
Whil…
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Analyzing Proteins Using SEC, MALS, and UHPLC
Light scattering analysis combined with more rapid size exclusion chromatography improves protein characterization.
The characterization of proteins involves identification of their complex …
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Evaluating the Use of Continuous Chromatography
…tography system can be loaded continuously, which is a useful approach when the purification step is connected to an upstream perfusion or fed-batch bioreactor, and, by having two or more columns in …
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Advances in Sterilization Technologies for Overcoming Viral-Vector Manufacturing Challenges
Sterility must be assured for all biologic drug products. Terminal sterilization achieved via treatment with heat, radiation, or certain chemicals (vaporous hydrogen peroxide, vaporous peracet…