Search results for " process"
Article
Top Challenges to Overcome When Developing AAV Processes: Part 1 of 2
Topics covered include:
1:00 – Two main challenges for upstream AAV process development, including which development platform to use and scalability
3:09 – Parameters evaluated for AAV p…
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Process Development: Go Smarter, Go Faster! Available on Demand
We heard from leaders at GlaxoSmithKline, Byondis, UCB, UCL, GoSilico, and Cytiva on how they balance innovation, speed, and robustness to accelerate their process development.
The upstream and …
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Virtual Scientific Symposium: Process Development: Go Smarter, Go Faster!
In this free virtual symposium, you'll hear from leaders at GlaxoSmithKline, Byondis, UCB, UCL, GoSilico, and Cytiva on how they balance innovation, speed, and robustness to accelerate their process d…
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Selecting Chromatography Formats for Your Process Development Workflow
The quality-by-design initiative by the FDA puts additional demands on process development work because a higher degree of process understanding is needed.
Therefore, the choice of tools is critic…
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Case Study: Process for Production of Oncolytic Adenovirus
Here, we present a case study from a biomanufacturer developing a process for adenovirus oncolytic adenovirus production. The case study describes a process from upstream cell culture to downstream pu…
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Utilization of Mechanistic Modeling to Improve Process Development
Utilization of mechanistic modeling of unit operations, based on scientific and physical understanding of the process, is one of these approaches. Improved computational resources in the past decade h…
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Welcome to the new Process Development Forum
The site is now organized around four main categories:
• Quality by Design
• HTPD
• Biosimilars
• Process Development
Each category features a comprehensive collection of artic…
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Selected courses from cell culture and downstream process development to scale-up and manufacturing
Built upon our expertise in the biopharmaceutical and biotechnological industry, our course curricula cover theory, applications, instrument use, process development and software.
Examples of avai…
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Insights from process developers - top challenges in recombinant protein purification
This constantly evolving molecular diversity brings challenges in chromatography process development. In this article, we focus on the challenges in purifying recombinant proteins that lack affinity c…
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How to develop a scalable rAAV process
Here we present the latest updates to our work developing a scalable start-to-finish rAAV process. We produce and purify several serotypes, optimizing each step along the way. The key for a successful…