Search results for "chromatography" in Articles / App Notes
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Experience Compact Scalability
Cost and speed are critical components in biomanufacturing. Can you get a good balance between these two things for your purification tasks, whether you are developing a process or manufacturing at pi…
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An Analytical Approach to Biosimilar Drug Development
As a result, demand has increased for chromatography and mass spectrometry technology providers to design instrumentation, software informatics, and workflows to support protein analysis studies. In a…
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Analytical SEC: How Does Back Pressure Relate to Resolution?
High resolution in HPLC is not achieved by applying back pressure to the column. Let’s straighten out what really helps you achieve high-resolution analytical SEC data.
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Bispecific Antibody Purification: Insights and Case Studies
New modalities, like bispecific antibodies, present unique challenges compared to mAb production. For purification, there’s not just one right answer to which strategy to use. Here are some industry…
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Four Purification Steps with Buffer Dilutions in One Go? No Problem!
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Free up time by automating the protein purification and by reducing manual interactions. Learn how Shin Isogai at Biozentrum, Basel, harnesses automation to puri…
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Scalable Viral Vector Manufacturing
For example, single-use bioreactors, filtration, and chromatography techniques are suitable for virus production.
Due to the diversity of viruses, platform solutions are challenging to implement e…
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Using Multiple Techniques in Biosimilar Analysis
Similarly, for reporting on quaternary structure, analytical ultracentrifugation (AUC) and size-exclusion chromatography with multi-angle static light scattering (SEC-MALS) are commonly used orthogona…
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Prepare for an FDA Bioburden Inspection
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Not sure how to best approach a bioburden problem when an FDA inspection is imminent? Anastasia Lolas, former FDA Biologics License Application (BLA) revi…
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Understanding Validation and Technical Transfer, Part 2
Qualification protocols are used for process equipment, such as tanks, mills, piping systems, autoclaves, ion exchange units, chromatography columns, and stopper washers. Validation protocols are used…
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Understanding Validation and Technical Transfer, Part 3
Any purification procedures and processes, such as recrystallization, chromatography, and viral clearance or inactivation, should likewise be characterized and defined. Cell lines, fermentation proces…