Search results for "chromatography" in Articles / App Notes
Article
Connect Alias™ Autosampler to ÄKTA™ Pure or ÄKTA Avant
To minimize manual injections and save time, an autosampler can be connected to your chromatography system. The autosampler enables fast injections of large number low volume samples.
Learn how to…
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Biopharma in 2015: A Year for Approvals and Innovations
…pharmaceutical manufacturing of bulk drug substances
FDA Approves First Biosimilar
Continuous chromatography in downstream processing of a monoclonal antibody
Highly efficient inoculum prop…
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Educational Protein Purification Videos
Watch educational videos for different chromatography techniques and applications.
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Biopharma Advances Demand Specialized Expertise
Ultra performance liquid chromatography (UPLC) systems have improved resolution and sensitivity, while reducing run times. In addition, 2D high-performance liquid chromatography (HPLC)/high-resolution…
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A Bright Future for the Plasma Fractionation Industry
Improvements in more established process operations, such as filter press operation and chromatography processes, were also reported.
Among the quality and regulatory trends, Quality-by-Design (…
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Detecting Protein Aggregates and Evaluating their Immunogenicity
This technique helps link liquid chromatography or capillary electrophoresis electrospray (CESI) easily and allows orthogonal techniques to work together for better information content. With peptide m…
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Securing the Single-Use Supply Chain
…re once its facility was in place, sourcing only critical disposable components such as filters and chromatography sorbents. Although disposable systems do provide numerous advantages, such as reduce…
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Mechanistic Modeling: Does it Have a Future in Process Development?
For some unit operations, such as ion-exchange chromatography, mechanistic models are easily employed for prediction. However, when it comes to reverse-phase chromatography or HIC, the mathematical de…
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Concentrating Feed—an Applicable Approach to Improve Antibody Production
Antibody titer was measured using high-performance liquid chromatography (HPLC) (Waters Corporation) equipped with a protein A column (Applied Biosystems). The protein charge profile was analyzed by i…
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Predicting Progress in Protein Aggregation
Some examples include modified immunoassays, self-interaction chromatography, and visual viscosity determination based on the diffusion of latex beads. “Unfortunately, there have been very few such te…