Search results for " media" in Articles / App Notes
Article
Ensuring Sterility in Small-Scale Production
Operator aseptic technique should be tested through the conduction of media fills representative of the actual manufacturing runs. At a minimum, media fills should be performed annually.
There als…
Article
Updated Ion Exchange Chromatography (IEX) Handbook
The update brings Sepharose and Capto IEX media together in the same book and the contents will ensure you get the most from your purification runs.
In addition to a new chapter on large-scale pur…
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Using Xcellerex™ mixing system as a slurry tank when packing chromatography columns
Further, an evaluation of the effect of the integrated, disposable mixer bag impeller on chromatography media particles was performed. The results show that XDM Quad Mixing System is suitable for use …
Article
Handbook: Size Exclusion Chromatography Principles and Methods
The media available, selection criteria and examples with detailed instructions for the most common applications are included, as well as the theoretical principles behind the technique. The first ste…
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SEC in the Modern Downstream Purification Process
Another recent advance in SEC resin development is the core shell or restricted-access media. In these cases, the resin matrix in the pore is modified with ionic charges, affinity ligands, or even hyd…
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Bioprocessing Advances in Vaccine Manufacture
Using the same manufacturing systems and culture media, these new systems produce the same amount of product at commensurately lower cost and often much faster. This higher yield has lead to US biodef…
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Sterilization Trends for Single-Use Consumables
Single-use (SU) technologies increasingly find use today at all phases of the drug development cycle from preclinical to commercial manufacturing. As the biopharmaceutical market continues to …
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Considerations in depth filter scale-up
The filter media thickness, pore size distribution, and adsorptive capacity make them the ‘go-to’ technology in harvest applications where a product is separated from a complex cell culture fluid.
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A Look into Biologic Scale-Up Strategies
To maximize cell-culture output, strategy is required that takes into consideration factors such as cell culture media, environmental monitoring, and process controls. Yet, despite decades of process …
Article
Future-proof your AAV process with a complete producer cell line – just induce and grow
… bioreactors
• Learn how Cytiva can help you optimize your upstream processing — with cells, media, bioreactors, and filters that work in tandem
Watch the webinar and learn more