Search results for " media" in Articles / App Notes

Article A Q&A on Bioprocessing Trends and Technologies at INTERPHEX 2016
Did you see any trends in the consumables segment? The quality and supply of cell-culture media, buffers, and other process liquids was also a popular topic. Demand for custom formulations and pac…

Article Lessons Learned Accelerate Vaccine Development
High-throughput and single-use technologies are also being leveraged to accelerate key aspects of manufacturing processes, such as determination of appropriate media, resins for purification, formulat…

Article A Risk-Based Genetic Characterization Strategy for Recombinant CHO Cell Lines Used for Clinical and Commercial Applications
Changes in media components and growth conditions often result in changes in cell culture profiles, and one should consider re-testing the integrity and stability of the expression construct at the li…

Article Developing Cleaning-in-Place Protocols
Cleaning conditions for chromatography media can be screened in a couple of working days using 96-well microtitre plate formats. A study with a Protein A resin illustrates the approach in this appli…

Article Selecting the Right Viral Clearance Technology
By Cynthia Challener, PhD The introduction of adventitious viral agents is a recognized, inherent risk of biologic drug production that is well addressed by international regulatory requirements…

Article CMOs Continue to Improve Overall Biomanufacturing Performance
These range from better analytical testing and product release services to better operations staff training, optimized media and improved existing quality management systems. Better process developmen…

Article Applications of Surface Plasmon Resonance for Detection of Bispecific Antibody Activity
(Springer Science+Business Media, New York, NY, 2012), pp. 9-32. 4. D.C. Swinney and J. Anthony, Nat. Rev.Drug Discov. 24, pp. 507-519 (2011). 5. M. Mitchell, BioPharm …

Article Host-Cell Protein Measurement and Control
Jun 01, 2015 By Fengqiang Wang, PhD, Daisy Richardson, Mohammed Shameem BioPharm International Volume 28, Issue 6, pg 32–38 Host-cell proteins (HCPs) constitute a major part of proce…

Article Optimization of Protein Expression in Escherichia Coli
May 01, 2015 By Siavash Bashiri, David Vikström, Nurzian Ismail BioPharm International Volume 28, Issue 5 Production of proteins for manufacturing therapeutics and pharmaceuticals is a c…

Article Continuous Chromatography: Trends, Definitions and Approaches
…pically enough, and that the addition of an extra column will only marginally improve chromatography media capacity utilization. Having said that, it is of paramount importance to realize that any mu…

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