Search results for " efficiency" in Articles / App Notes
Article
Mixing dynamics in a large volume single use mixer
Large-volume mixers are mainly required in clinical three-scale and production-scale facilities where mixing efficiency is one of the key drivers of throughput efficiency. Upstream applications such …
Article
Generating a Fully Processed Antibody
High gene insertion efficiency
The ability to efficiently insert genes into cells makes balancing ratios of protein expression a much easier process and shortens timelines. Complex protein molecul…
Article
Platform Approach Speeds Process Development
… becomes an issue because the drug substance must be produced in large quantities with cost and time efficiency to meet clinical requirements and pave the way toward commercialization.
Within the…
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Tools for Continuous Bioprocessing Development
Could perfusion microbioreactors bring more agility to biomanufacturing?
By Rajeev J. Ram
In semiconductor manufacturing, for example, a thorough understanding of process variation allows co…
Article
Modern Manufacturing Systems Key to FDA Quality Initiative
Apr 02, 2015
By Jill Wechsler
Pharmaceutical Technology
Volume 39, Issue 4
To ensure patient access to high quality, safe, and effective medicines, FDA spends considerable time and resou…
Article
Technologies and Practices Must Evolve to Meet Demand
More than 76% of the 2015 respondents reported improved process understanding; nearly 60% cited increased efficiency or reduced waste as a result of implementing QbD. Barriers to implementation remain…
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Optimizing Resin Performance with Disposable Chromatography Solutions
Where we have seen significant advances in chromatography is with innovative new Protein A-derived media that are delivering improved capacity and stability, helping to increase production efficiency,…
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New Era for Generic Drugs
Manufacturers face regulatory overhaul, while brand-generic debates escalate over biosimilars and labeling changes.
Nov 1, 2014
By: Jill Wechsler
BioPharm International
Volume 11, Issue …
Article
A Q&A With Dr. Anurag Rathore About the Future of QbD, Part I
This two-part Q&A series with Anurag Rathore, PhD, Professor, Department of Chemical Engineering, Indian Institute of Technology, Delhi, reveals the evolution of QbD, the types of companies implemen…
Article
Analyzing Proteins Using SEC, MALS, and UHPLC
“Understanding the aggregate content is important because aggregates not only consume monomers and thus reduce the efficiency of the drug, they also are believed to cause immune responses. Thus, even …