Search results for " efficiency" in Articles / App Notes
Article
Regulatory Challenges in the QbD Paradigm
The authors demonstrate how an integrated model is helping to achieve regulatory flexibility. This article is part of a special section on biopharmaceutical trends.
With the dawn of the 2…
Article
Automated Concentration and Diafiltration of Multiple siRNA Samples
The project objective was to streamline the process to improve process efficiency and productivity while improving product quality.
PROCESS DESCRIPTION
The production of RNA ol…
Article
Addressing the Challenges in Downstream Processing Today and Tomorrow
Newer classes of biotherapies will require innovations in processing technology.
By Glen R. Bolton, Bernard N. Violand, Richard S. Wright, Shujun Sun, Khurram M. Sunasara, Kathleen Watson, Johna…
Article
Under pressure: exploring root causes of leaks in single-use mixers
But efficiency isn’t just about what your equipment can do – it’s also about how well it performs and scales up. Equipment failures in large-scale bioprocess can be costly in terms of material loss an…
Article
Free eBook: Considerations for smarter and faster process development
Biopharmaceutical Process Development -
Considerations for Smarter and Faster Process Development.
What you will learn:
Industry drivers to go smarter and faster in process de…
Article
Optimizing capture and polishing steps in an rAAV purification process
In this article, we show how we developed an efficient purification process for recombinant AAV (rAAV). The chromatography purification described includes affinity capture to maxi…
Article
Cell-free Expression Systems Pose Cell Culture Alternative
During a short period of time, the system can make protein biologics with high efficiency with minimal by-products, and you don’t have to worry about proteolytic of recombinant protein caused by prote…
Article
Innovative Chromatography Resins Can Improve Purity and Quality
By: Feliza Mirasol
Recent innovations in chromatography resins offer promising advantages in downstream bioprocessing.
With ongoing efforts to increase monoclonal antibody (mAb) productivi…
Article
Eliminating Residual Impurities Starts with a Strategic Plan
Monitoring the efficiency of the residual impurities will be guaranteed through the development of robust analytical methods,” he explains. Savoy also recommends that methods be developed following an…
Article
Gene Therapies Push Viral Vector Production
Compared to adenovirus and AAV, retrovirus-based vectors show relatively low transduction efficiency in-vivo, but their advantage lies in their ability to integrate stably and confer long-term transge…