Search results for "continuous"
Article
ADC Development Robust Despite Lackluster Performance
ADC Development Robust Despite Lackluster Performance
Despite the disappointing therapeutic performance of ADCs thus far, the pipeline still boasts promising prospects.
By Feliza…
Article
Modeling and Miniaturization: Key Topics at Successful HTPD Conference
Modeling and miniaturization were two key take-home messages from the 4th High Throughput Process Development (HTPD) conference organized in October 2017 in Toledo, Spain. The conference brought tog…
Article
Bioburden Control in the Biopharmaceutical Industry
Thus, a continuous microbiological monitoring plan, coupled with SPC, should be used to assess the current state of bioburden reduction and control and to determine the improvements that are necessary…
Article
Cost Considerations Drive Lean Technology in Biopharmaceutical Manufacturing
Taken together, upstream and downstream process innovations can be packaged into an automated, continuous, small-footprint antibody production facility that can fit into a single cabinet in approximat…
Article
Managing Risk in Raw Material Sourcing
“Our efforts are focused on compliance with the International Council for Harmonization’s (ICH) Q7 (for APIs) and IPEC (for bulk pharmaceutical excipients) guidelines to continuously improve our syste…
Article
Innovation vs. Capacity: How CMOs Compete
The strategies of an innovation-driven CMO may be different than a capacity-driven CMO.
By Jim Miller
While industry participants and observers talk about the “CMO industry,” they know that …
Article
Safety Drives Innovation in Animal-Component-Free Cell-Culture Media Technology
This is especially impressive when contrasted to the native environment of animal cells, which is generally a complex, protein-rich, milieu of thousands of 100% animal-sourced compounds continuously p…
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Managing Biomanufacturing Capacity Expectations
BioPlan found that the development of more efficient single-use products, better downstream purification technologies, the introduction of continuous downstream operations, and increased modularizatio…
Article
Biosimilars: Making the Switch Comes with Challenges
More efforts are needed to raise awareness of biosimilars among physicians and patients in Europe and address scepticisms about the quality and safety of biosimilars.
By Sean Milmo
The use o…
Poster
Unlocking the potential for efficiency in downstream bioprocesses
It describes techniques like continuous processing and in-line conditioning buffer preparation, system automation, and more. It also shows how implementation of efficient process designs can overcome …