Search results for " platform"

Article Downstream Processing for Cell-Based Therapies
Current available DSP platforms generally offer either high specificity or high throughput, but rarely both. While highly specific labeling separation systems may be suitable within low volume product…

Poster FlexFactory™ Automation
This automation platform is the foundation of the flexible, configurable, and scalable FlexFactory biomanufacturing solution. The FlexFactory biomanufacturing solution can be delivered as either an in…

Article Biopharma in 2016: Higher Quality Drugs, Less Expensive Manufacturing
…rned Accelerate Vaccine Development Overcoming Buffer Challenges With In-Line Conditioning A Platform Approach to Purification of Antibody Fragments References 1. Walker, Nigel, Innov…

Article Design and Qualification of Single-Use Systems
… fitment (leak) integrity properties, sterilizability, drainability, incorporation into an automated platform as the disposable fluid path, etc. • Manufacturability ensures that the SUT productio…

Article Vaccine Development Faces Urgency and Challenges
…urther the development and manufacturing of new Zika vaccine candidates and other innovative vaccine platform technologies. BARDA already is working with Brazilian agencies to develop a Zika vaccine …

Article Antibody Production in Microbial Hosts
Glycoengineering platforms, display technologies and library creation, and robust manufacturing process development support the use of microbial cells as suitable candidates for pharmaceutical develop…

Article Selecting the Right Viral Clearance Technology
…erally used to understand the clearance potential of a step that will be included in a manufacturing platform. Lot-to-lot-variation in both product feedstocks and consumables is another factor th…

Article Applications of Surface Plasmon Resonance for Detection of Bispecific Antibody Activity
Bispecific antibodies are also considered an effective platform for the delivery of therapeutic antibodies across the blood-brain barrier (2). This suggests that in certain cases, bispecific antibodie…

Article Taking a “Development-by-Design” Approach to Cell Therapies
to use its Mobius bioreactor platform to expand and harvest HepRG cells. Cytiva is also evaluating Wave and other systems and set up a center of excellence in Wales recently. In other equipment ar…

Article Biosimilars Will Bring Significant Litigation and Patent Challenges
Fuller adds that the immunogenicity risks associated with biosimilars could relate to their formulation and technology platforms, “but the specific patents will not be known, as the originator will no…

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