Search results for " platform"
Article
Recent Advances in the Use of Exoglycosidases to Improve Structural Profiling of N-glycans from Biologic Drugs
In the coming years, it is anticipated that similar capabilities will become the norm in software packages associated with commercial glycoanalytical platforms.
Figure 3. Exa…
Article
Manufacturing of Viral Vectors
As a vaccine platform, viral vectors can be used for the expression and presentation of pathogenic antigens to induce an immune response by mimicking a natural infection. Viral vectors can also be use…
Article
Transformative Medicines Challenge FDA and Manufacturers
Presentations covered the importance of control strategies and the need to characterize and qualify impurities, including the use of platform data in assessing oligo impurities.
Firoz Antia, d…
Article
Reliability Rooms and the Move to Proactive Supply Chain Management
The EDW is built on a Teradata platform, and staged data are visualized and analyzed using a number of different software programs, including products from Spotfire, Tableau, Qlikview, and Qliksense.
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Article
Roadmap Leads to Innovative Biomanufacturing Strategies
Also, many aspects of the Biomanufacturing Technology Roadmap are not specific to any specific manufacturing platform. Issues such as automation standards, supplier partnerships, knowledge management,…
Article
Modeling and Miniaturization: Key Topics at Successful HTPD Conference
Breinlinger presented a platform that could automate cell line development by operating single cells in a nanofluidic environment. Using light, single cells were isolated in individual nanoliter-sized…
Article
Manufacturing Standards Key to Advancing Cellular and Gene Therapies
Bryan Silvey, senior director for quality compliance at Kite Pharma, emphasized that personalized cell therapy production, utilizing a “one lot-one patient” manufacturing platform with a 15-d…
Article
The New World of Biopharmaceutical Manufacturing
Companies are implementing end-to-end single-use platforms for monoclonal antibody, antibody drug conjugate, and vaccine production. Flexible facilities are likely to become an important part of large…
Article
N-Glycan Analysis of Biotherapeutic Proteins
These new platforms are coupled with software to assist in peak integration, peak calling, and determination of relative abundance, allowing many samples to be processed in a single day. Ease and spee…
Poster
Development of DoE based fed-batch strategies for high-producing CHO cell cultures
Typical standard platform processes rely on fixed-volume bolus feeding of concentrated supplements at regular intervals. However, such static approaches might result in over- or underfeeding. To mimic…