Search results for " yield"
Article
Efficient Purification of Pneumococcal Polysaccharides in a Chromatography Workflow
…l polysaccharides to eliminate the need for phenol extraction, while increasing process recovery and yield.
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Article
A Platform Approach to Purification of Antibody Fragments
The described BioProcess™ resins offer high selectivity and excellent pressure-flow properties for high purity and yield in industrial-scale purifications. In addition, several case studies on purific…
Poster
Guide to modern BioProcess™ chromatography resins
Based on what protein you would like to purify and the conditions used, chromatography resins are selected to optimize purity and yield. Many bioprocess applications include three chromatography steps…
Poster
Scale-up of CHO fed-batch cultures in HyClone™ ActiPro™ medium supplemented with Cell Boost™ 7a and 7b
Protein yields reached as high as 5 g/L in shake flasks, and as high as 5.5 g/L in bioreactor cultures.
Article
Modeling Bioreactor Performance
Analyzing with simulation scenarios, fluid processing and sequencing may yield more practical near-term results than coming up with a novel bioreactor design through modeling,” he notes.
Typically…
Article
Safety Drives Innovation in Animal-Component-Free Cell-Culture Media Technology
The new expectations challenged biologics producers to avoid all animal-sourced materials in any new processes without sacrificing the high yields and overall process performance that were commonly co…
Article
Perfusion in the 21st Century
Quality, flexibility, and cost savings are driving use of perfusion technology in biosimilars manufacturing.
By Bruce Lehr, Delia Lyons
Cell-culture technology for biopharmaceutical manufact…
Article
Downstream Processing Continues to Worry CMOs
Downstream continues to fail to keep up with the recent advances in upstream yield and titers.
Reference
1. BioPlan Associates, 13th Annual Report and Survey of Biopharmaceutical Manufacturi…
Article
Microbiological Testing: Time is of the Essence
Pressures to accelerate current and next-gen therapies are challenging traditional microbiological testing methods.
By Cynthia A. Challener
Effective microbiological testing during biopharmace…
Article
Fast Turnaround with Automated Column Packing
Packing success is, therefore, key to ensure an efficient purification process with high yield and throughput.
Packing success from the start
Today it is possible to get packing right on the f…