Search results for "antibody" in Articles / App Notes
Article
Get Acquainted with How SPR Technology is Used for Better Protein Characterization
Surface plasmon resonance (SPR) has become a go-to tool for biotherapeutic characterization, and most approved antibody therapeutics have passed through a Biacore SPR system.
Stay up-to-date wit…
Article
Cleaning Protein A Resins with 1 M NaOH
With increasing mAb titers, the impurity level of the cell culture feed increases. If not removed, these impurities can build up on the protein A resin and start to leach into the process material i…
Article
Chromatography Scale-Up: Don’t Get Tied Down by Bed Height
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When scaling, you can make better use of existing chromatography columns while avoiding overcapacity.
Keeping a constant residence time is a well-est…
Article
NIST Spectroscopic Measurement Standards
…surements by providing an industrially relevant reference material, a well-characterized monoclonal antibody.
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Peer-Reviewed
Submitted: Jan. 22…
Article
Making the Move to Continuous Chromatography
Making the Move to Continuous Chromatography
Early adopters are benefiting from lower costs and increased productivity.
By Cynthia A. Challener
Tashatuvango/Shu…
Article
Understanding Validation and Technical Transfer, Part I
Understanding Validation and Technical Transfer, Part I
This is the first of a series of three articles about validation and technical transfer in the bio-pharmaceutical industry. Part 1 || Part 2 |…
Article
Your Protein Purification Questions Discussed
In one of Cytiva´s web chats, ÄKTA™ system users asked questions relating to lab-scale protein purification and ÄKTA systems, which experts answered during a live session.
The expert…
Article
Roadmap Leads to Innovative Biomanufacturing Strategies
Roadmap Leads to Innovative Biomanufacturing Strategies
The Biomanufacturing Technology Roadmap is accelerating innovative manufacturing strategies for biopharmaceuticals.
By Feli…
Article
Reducing Cross-Contamination Risks in Process Chromatography
…d in particular for the production of biologic drug substances with high cytotoxic potency, such as antibody-drug conjugates (ADCs), according to Morelli. In Lundström’s experience, in addition to hi…
Article
Performance of Single-Use Xcellerex™ XDR‑500 MO and XDR‑50 MO Stirred-Tank Fermentor Systems
Domain antibody production in E. coli was used as the model process. Fermentations were performed as fed‑batch processes, with glycerol feed and a two‑stage induction strategy. The presented data …