Search results for "pcc" in Articles / App Notes
Article
Continuous Processing for the Production of Biopharmaceuticals
For instance, in the case of chromatography, the available batch protocol can be run using periodic counter-current chromatography (PCC) with modification made to the process parameters to match the r…
Article
Maximize resin usage with continuous bioprocessing
Periodic counter-current chromatography (PCC) is a multi-step approach to maximize the chromatography resin capacity utilization and minimize process time. The technology employs three or more chromat…
Article
Continuous Chromatography: Trends, Definitions and Approaches
There is a lot of attention being paid to continuous chromatography, and several different terms are being used: SMB, PCC, MCC. What is your view on the terminology? Is there a difference among them? …
Article
Making the Move to Continuous Chromatography
There are several different techniques available, including simulated moving bed (SMB) and periodic counter current chromatography (PCC). The aim is the same for all: to achieve a continuous (over) lo…
Article
Technology Innovations Improve Process Chromatography Performance
Hardware innovations, such as simulated moving bed (SMB), periodic counter-current (PCC), or other systems, which allow users to make more efficient use of a resin are still emerging, he adds.
“We…
Article
Integrated Semi-Continuous Process for mAb Production
A complete process for the production of a biopharmaceutical consists of a great number of distinct unit operations, for example, cell culture, filtration, and chromatography. Linking these differen…
Article
What You Need to Know about Continuous Processing
There is a lot of interest around continuous biomanufacturing, and it is expected to have a significant impact on the biomanufacturing industry over the next few years. Continuous processing can hel…
Article
Process Chromatography Selection for Downstream Processing Applications
Periodic counter current chromatography (PCC) allows overloading of columns and continuous loading at the same time. Arranging two different modes of chromatography in series, operated with or without…
Article
Continuous Manufacturing: A Changing Processing Paradigm
Apr 01, 2015
By Randi Hernandez
BioPharm International
Volume 28, Issue 4
Although continuous manufacturing is well established for bulk chemicals, complex automation and validation …