Search results for " harvest"
Article
Best Practices in Adopting Single-Use Systems
Key considerations for implementing single-use components or platforms when moving from research to process development.
The adoption of single-use systems in biopharmaceutical production or…
Article
Comparing Protein A Resins for Monoclonal Antibody Purification
As a consequence, downstream processing must accept and handle higher titers of mAbs in harvested cell-culture fluid (HCCF), and vendors of mAb purification technologies must develop chromatography re…
Article
HT Multi-Product Liquid Chromatography for Characterization of Monoclonal Antibodies
2-dimensional Protein A–size exclusion chromatography to evaluate cell line product titer and aggregate levels in harvested cell culture fluid. AAPS Annual Meeting. 2007.
Article
PDA's Technical Report for Biotech Cleaning Validation
However, residues used for spiking surfaces for recovery studies in biotech cleaning validation may include not only the bulk active, but also soils representative of early-stage harvesting steps. Fur…
Article
Addressing the Challenges in Downstream Processing Today and Tomorrow
Most companies have developed standardized purification processes typically consisting of a cell harvest method followed by a capture chromatographic step and one or polishing steps. The approach used…
Article
Quality by design for biotechnology products—part 1
…bility, and glucose concentration may be affected by the inoculum, medium, bioreactor operation, and harvest. Scientific understanding and prior knowledge can be used together with quality risk manag…