Search results for " techniques" in Articles / App Notes
Article
Capto™ Core 700 in Vaccine Processing
The aim with this white paper is to discuss the advantages of using Capto Core 700 in virus purification compared to size exclusion chromatography (SEC), a technique commonly used in several vaccine…
Article
Advanced Technologies Facilitate Scale-up and Technology Transfer
Galliher sees both advantages and disadvantages associated with continuous processing, and he remains uncertain whether these techniques and technologies will graduate to the commercial manufacturing …
Article
Continuous Manufacturing: A Changing Processing Paradigm
Elements such as product and process compatibility with available technologies, as well as product and market demand, could factor into the decision to incorporate continuous techniques in biological …
Article
Handbook: Size Exclusion Chromatography Principles and Methods
This handbook describes the use of SEC for the purification and separation of biomolecules, with a focus on practical information for obtaining the best results. The media available, selection crite…
Article
Securing the Single-Use Supply Chain
“These results indicated that the materials were comparable within the variability of the analytical techniques used,” Briggs says. He also recognizes that tubing is a universal single-use component, …
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High-Throughput Process Development in an Historical Environment
As an example, John Welsh from Merck presented a collaboration with Cytiva on the development of the next- generation multimodal chromatography resins and how high throughput techniques and different …
Article
Evaluating Design Margin, Edge of Failure and Process
Design space generation is encouraged in new product development.
Sep 1, 2014
By: Thomas A. Little, PhD
BioPharm International
Volume 27, Issue 9, pp. 46-49
A product’s or proc…
Article
Concentration and Diafiltration of Cell-Derived, Live Influenza Virus Using 750 C Hollow Fiber Filter Cartridge
Cross flow filtration (CFF) is a technique extensively used in vaccine production and particularly in influenza vaccine manufacturing. In contrast to normal flow (dead-end) filtration (NFF), the fee…
Article
Applying GMPs to the BioPharma Supply Chain
Capabilities will need to be developed and tools and techniques learned. The drivers for change are powerful and unrelenting, but biopharmaceutical companies are ready for the challenge.
At some p…
Article
Challenges in Analytical Method Development and Validation
…are, critical reagents, standards, controls, and analysts who are skilled in the relevant analytical techniques as well as the qualification status of all materials, equipment, and analysts.
If g…