Search results for " techniques"
Article
The Need for Advanced Process Modeling for New Therapeutic Biologics
Sinclair notes that there are specific challenges to some of the newer personalized therapies and gives the following examples of modeling techniques that can be broken into several areas:
…
Article
Biosimilar Quality Requirements
For higher-order structural analysis, various biophysical techniques are mainly employed, according to a paper published by M. DiPaola and I. Javeri (5).
Mass spectrometry has been known as a key …
Article
Driving Improved Access to Biosimilars
Bioanalytical techniques and associated software have become much more powerful, and far beyond what was available in the early days of innovator molecules, Magil says, and techniques such as mass spe…
Article
Moving PAT from Concept to Reality
Sartorius Stedim Biotech also believes that spectroscopic techniques will become more abundant in both upstream and downstream bioprocessing, due to its capability of label-free, online measurements o…
Article
Emerging Therapies Test Existing Bioanalytical Methods
…ut lacks any specifics on assays that use flow cytometry, PCR, protein expression/activity, or other techniques. This leaves investigators asking questions about how to demonstrate the key bioanalyti…
Article
An Analytical Approach to Biosimilar Drug Development
Providing analytical data on the comparison between a biosimilar and the reference product is a primary consideration in the development of biosimilars.
By Feliza Mirasol
…
Article
A Look at the Affinity Chromatography Landscape
He does note that the use of standard and multimodal resins and high-throughput screening technologies greatly aid in defining separation techniques.
Most importantly, Heldin adds that affinity…
Article
Ensuring Viral Safety of Viral Vaccines and Vectors
Beyond these tests, other techniques for the detection of retroviruses may be implemented. Retrovirus particles can be detected using transmission electron microscopy (TEM). Reverse transcriptase enzy…
Article
Generate an Automated Purification Protocol in Three Steps Using Predefined Methods
Regardless of the chromatography technique you are using or if you are using a combination of techniques, UNICORN™ software used for ÄKTA™ systems provides years of purification experience built …
Article
Automation Trend in Fill/Finish Reduces Contamination Risk
Handling sterile liquids in the pharmaceutical industry has traditionally relied on consistent techniques over the past 100 years, and changes in technology and regulations have been relatively slow, …