Search results for "perfusion"
Article
Designing a Biomanufacturing Facility Incorporating Single-Use Technologies
Figure is courtesy of Cytiva
Starting with upstream, the status of the cell line and whether the process should be batch, fed-batch, or perfusion needs to be decided. Details about the nature of…
Article
Biopharma in 2015: A Year for Approvals and Innovations
…aphy in downstream processing of a monoclonal antibody
Highly efficient inoculum propagation in perfusion culture using WAVE Bioreactor™ systems
The Use of Dynamic Control in Periodic Counter-…
Article
Biopharma Advances Demand Specialized Expertise
…orimer (Patheon Biologics): Continuous production from mammalian cell cultures has been operated in perfusion bioreactors for many years. The main roadblock for continuous processing is downstream pr…
Article
Continuous Chromatography: Trends, Definitions and Approaches
Obviously, prevention of bioreactor contamination is of paramount importance if the reactor is operated in perfusion mode and is connected to a continuous chromatography system, but this can be realiz…
Article
What Drove Biopharma Development in 2014?
On the PDF site, this trend was evident based on webinar invitations, as well as in published application notes and articles, such as Highly efficient inoculum propagation in perfusion culture using W…
Article
The Future of Biopharma
…ion of single-use systems at clinical and commercial scale
• continuous processing, including perfusion
• high-tech expression systems and other genetic engineering advances
• automation,…
Article
Addressing the Challenges in Downstream Processing Today and Tomorrow
Cell culture was performed using numerous methods, including roller bottles and stirred tank bioreactors operated in perfusion, batch re-feed, or fed-batch mode (1).
Starting in 1986 with the lic…