Search results for " mammalian" in Articles / App Notes
Article
Challenges of Protein Aggregation During Purification
Cytiva recently announced a licensing agreement with Promosome, a company with a technology for improved protein expression in mammalian cells. “We have hope that Promosome’s technology will be a bett…
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Monoclonal Antibodies Key to Unlocking the Biosimilars Market
In addition, it is quite expensive to develop more complex biosimilar mAbs, as much as a $200 million investment for one candidate, including the necessary mammalian cell culture facility built in com…
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Trends in BioPharma Approvals in 2013
In terms of expression systems used, a total of eight of the products approved are expressed in mammalian cell lines (seven in CHO cells, one in Sp20), six are produced in yeast-based systems, four in…
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The Development and Application of a Monoclonal Antibody Purification Platform
Recent advances in mammalian cell culture technology have resulted in significant increases in upstream productivity, with antibody titers of >5 g/L becoming increasingly common. Such increases could …
Article
Milestones and Moderate Progress in 2012 Drug Approvals
These figures once again reflect the ongoing dominance of mammalian-based expression systems in terms of biopharmaceutical manufacture.
Digging a little deeper reveals that the majority …